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Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.

Steroid sulfatase inhibitors could help treat hormone-related disorders and cancers.

Efficient enzyme function relies on specific residue interactions and structural coordination.

Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.

OsPHR3 can help breed rice that efficiently uses phosphate without growth issues.

Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

Joint replacement surgery normalized high alkaline phosphatase levels in a patient with severe osteoarthritis.

PSAT1 is key for hair growth and stem cell function in cashmere goats.

PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.

PLDζ2 and NPC4 have different roles in lipid changes and root hair growth in Arabidopsis under low phosphate, with PLDζ2 reducing root hair growth and NPC4 promoting it.

Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.

MPZL3 protein helps control the size of oil glands and the growth of oil-producing cells in both mice and humans.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Skin tumor cells in patients with tuberous sclerosis have higher levels of a protein called cathepsin B.

The research found enzymes in Stephania epigaea that help make cepharanthine.

Overexpressing a specific enzyme in mice causes hair loss and female infertility.

Sesn2 protects inner ear hair cells from damage by regulating certain cell survival pathways.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Different sPLA2 enzymes have unique roles in phospholipid metabolism and biological processes.

Low TRPS1 expression in skin and hair cells is linked to hair problems in Trichorhinophalangeal syndrome.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Scientists found new, better-working inhibitors for a hormone-related enzyme.

LPAR6 has a unique way of binding and activating, which helps in designing treatments for hair loss and cancer.

Ceramide Synthase 4 is crucial for maintaining hair follicle stem cells and preventing hair loss.

5% minoxidil foam effectively regrows hair in women, with postmenopausal women seeing the most improvement.

New mutations in MBTPS2 reduce its function and cause IFAP syndrome with unusual symptoms.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

Phosphate starvation reduces calcium signaling in plant roots.

A new genetic variant causes BRESHECK syndrome by disrupting cell growth and stress response.

SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.