211 citations
,
May 2013 in “Journal of Nutrition Health & Aging” MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.
3 citations
,
August 2021 in “Uro” Saw palmetto may improve urinary symptoms with fewer sexual side effects compared to some medications.
14 citations
,
September 2019 in “Eye” Some oral medications may help treat central serous chorioretinopathy, especially eplerenone, but more research is needed.
16 citations
,
January 2003 in “Nuclear Receptor Signaling” Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
Saw palmetto extract is effective and safe for treating lower urinary tract symptoms, working as well as certain medications, and works even better in severe cases.
2 citations
,
May 2024 in “European Journal of Investigation in Health Psychology and Education” Many bodybuilders in Sergipe, Brazil use anabolic steroids, facing health risks like acne, irritability, and hypertension.
September 2018 in “Translational andrology and urology” MOTILIPERM may help treat male infertility by reducing stress in cells.
1 citations
,
November 2021 in “British Journal of Clinical Pharmacology” Saw palmetto may cause erectile dysfunction and needs better safety monitoring.
November 2011 in “InTech eBooks” Selenium shows promise in preventing and controlling prostate cancer.
May 2013 in “UTUPub (University of Turku)” Including androgens in hormone therapy may lower breast cancer risk.
3 citations
,
January 2018 in “Elsevier eBooks” Serenoa repens is a common and effective plant-based treatment for mild-to-moderate prostate enlargement symptoms.
5 citations
,
September 2024 in “Stem Cell Research & Therapy” Sertoli cell transplants can reduce inflammation and improve sperm quality.
1 citations
,
May 2023 in “Elsevier eBooks” 108 citations
,
April 2004 in “Medicinal Research Reviews” Steroid sulfatase inhibitors could help treat hormone-related disorders and cancers.
1 citations
,
January 2003 in “Urologia Internationalis” Finasteride, selenium, and vitamin E may help prevent prostate cancer.
72 citations
,
January 2011 in “Current Pharmaceutical Design” S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
306 citations
,
August 2011 in “Journal of cachexia, sarcopenia and muscle” Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.
October 2025 in “Scientific Reports” Serenoa repens extract shows promise as a natural treatment for prostate cancer.
January 2008 in “OhioLink ETD Center (Ohio Library and Information Network)” SARMs work differently in tissues due to unique interactions and structures.
11 citations
,
August 2009 in “Expert Opinion on Drug Discovery” We need better ways to test and understand SARMs to make safer and more effective treatments.
September 2012 in “DOAJ (DOAJ: Directory of Open Access Journals)” D-004 shows moderate antidepressant effects but is less effective than Sertraline and Imipramine.
4 citations
,
October 2023 in “Fertility and Sterility” Some medications and supplements can affect male fertility, with some improving and others harming sperm quality.
37 citations
,
September 2003 in “Journal of Medicinal Chemistry” A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
2 citations
,
July 2021 in “Uro” Saw palmetto extract is generally safe and can effectively treat Lower Urinary Tract Symptoms, but its evaluation is affected by varying quality and a need for long-term studies.
29 citations
,
February 2007 in “Hormone and metabolic research” Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
April 2020 in “Online journal of complementary & alternative medicine” Some medications can help increase sexual desire and function in women.
111 citations
,
August 2002 in “Journal of Medicinal Chemistry” New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
5 citations
,
September 2011 in “Bioorganic & Medicinal Chemistry Letters” Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
34 citations
,
December 2012 in “Current Opinion in Clinical Nutrition and Metabolic Care” Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.
December 2018 in “Reactions Weekly” Some medications may cause lasting sexual dysfunction.