April 2026 in “C&EN Global Enterprise” Serotonin's role in mental health is complex and not fully understood, affecting treatment effectiveness.
September 2025 in “Romanian Journal of Medical Practice” Iron deficiency is linked to female pattern hair loss.
January 2017 in “ScholarWorks - WMU (Western Michigan University)” Stopping SSRIs can reverse hair loss in some patients.
25 citations
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January 2006 in “Pharmacoepidemiology and drug safety” SSRIs can cause hair loss, especially sertraline, with higher risk in women.
22 citations
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January 1992 in “PubMed” Higher CSF 5-HIAA levels may predict better response to serotonin re-uptake inhibitors in trichotillomania.
19 citations
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March 1999 in “PubMed” Trichotillomania is a chronic condition where people uncontrollably pull out their hair, often starting in childhood.
18 citations
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September 1972 in “British Journal of Pharmacology” PCPA induces hypersexual behavior in male rats regardless of age or castration status.
15 citations
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September 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” Skin doctors should recognize and treat conditions like hair-pulling and skin-picking early, often using therapy and medication, to help 50-70% of patients.
11 citations
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November 1991 in “Journal of Neuropathology & Experimental Neurology” Brindled mice show abnormal catecholamine neuron development due to copper deficiency.
8 citations
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November 2011 in “Journal of Medical Case Reports” Bupropion may help treat trichotillomania when fluoxetine doesn't work.
February 2026 in “Molecules” A new method can quickly and accurately measure tobacco exposure and stress using a small hair sample.
December 2025 in “Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)” This systematic review evaluated the effects of Botulinum toxin type A (BoNT) on biochemical biomarkers in head and neck chronic conditions associated with inflammation. Nine studies were included, with concerns about bias in six. The most frequently studied biomarker was the calcitonin gene-related peptide (CGRP), followed by serotonin. Significant effects of BoNT were reported in six studies, including decreased plasma levels of CGRP in chronic migraine and trigeminal neuralgia, changes in serotonin levels, and alterations in oxidative stress and inflammatory markers. Despite these findings, the evidence was rated as very low to moderate certainty.
New substances were created that improve health and may treat dementia, osteoporosis, and cancer.
November 2023 in “International journal of biology, pharmacy and allied sciences” Banana plants have many health benefits, but more research is needed to confirm them.
March 2020 in “European Journal of Pediatric Dermatology” Isotretinoin can cause gynecomastia by lowering testosterone levels.
January 2017 in “International journal of science and research” Trichotillomania is a chronic hair-pulling disorder, more common in females, treated with therapy and sometimes medication.
83 citations
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January 2001 in “American journal of clinical dermatology” Clomipramine may significantly reduce hair-pulling in Trichotillomania, but more research is needed on treatments and early onset cases.
38 citations
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April 2017 in “Journal of The American Academy of Dermatology” Many skin patients have mental health issues, but few dermatologists are well-versed in treating these conditions.
30 citations
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August 2018 in “Dermatology and Therapy” Better-designed, long-term studies are needed to optimize treatment for trichotillomania and trichophagia.
25 citations
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January 2015 in “Advances in Psychosomatic Medicine” Many skin patients also have mental health issues, and doctors should treat both together.
17 citations
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February 2011 in “Expert Opinion on Drug Safety” Manage side effects of hepatitis C treatment with dose changes and medications, which may improve patient adherence and treatment success.
8 citations
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January 2016 in “Case Reports in Psychiatry” Trichotillomania in dementia may be better treated with dopamine blockers like quetiapine than with SSRIs.
6 citations
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December 2008 in “Clinics in Dermatology” Escitalopram might effectively treat delusions of parasitosis and possibly Morgellons disease, with psychological factors being important to consider.
5 citations
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February 2013 in “Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology” A teenager lost hair due to fluoxetine and sertraline, but it grew back after stopping these drugs and switching to a different one.
4 citations
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January 2019 in “Clinical and Experimental Dermatology” The review found that individualized treatment and teamwork are important for trichotillomania, and patients who followed through with treatment often improved.
3 citations
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May 2018 in “Psychiatry and Clinical Psychopharmacology” N-acetylcysteine may help treat trichotillomania.
3 citations
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January 2016 in “International Journal of Contemporary Pediatrics” Children with trichotillomania often pull hair from their scalp and may have other mental health issues.
3 citations
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December 2001 in “Irish Journal of Psychological Medicine” Trichotillomania is a challenging-to-treat impulse-control disorder where individuals pull out their hair, more common in females, with some treatments showing benefits.
2 citations
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July 2005 in “Baylor University Medical Center Proceedings” A 4-year-old girl was diagnosed with trichotillomania, a condition where she pulls out her hair, which may resolve on its own or require therapy.
1 citations
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September 2025 in “Pediatric Dermatology” Behavioral interventions, especially habit reversal training, are most effective for treating trichotillomania in children.