research Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry
Multitarget drugs are needed to better treat complex diseases.
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research Pregnenolone for the treatment of L-DOPA-induced dyskinesia in Parkinson's disease
Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.
research The role of vitamin D for the management ofdepression in patients with autoimmune thyroiditis andhypothyroidism in the West-Ukrainian population
Vitamin D can help reduce depression in people with hypothyroidism.
research The Men’s Training Cup Keep Training: a masturbation aid improves intravaginal ejaculatory latency time and Erection Hardness Score in patients who are unable to delay ejaculation
The Men's Training Cup Keep Training masturbation aid may help delay ejaculation and improve erectile function.
research The role of vitamin D for the management of depression in the Western Ukrainian population with autoimmune thyroiditis and hypothyroidism
Vitamin D helps reduce depression in people with autoimmune thyroiditis and hypothyroidism.
research The effects of methylated flavonoids on depression-like activity and pro-inflammatory cytokine thresholds in mice induced by repeated finasteride administration
Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.
research Depressive and Anxiety Symptoms in Women with Polycystic Ovary Syndrome: A Meta-Analysis
Women with PCOS are more likely to experience depressive symptoms.
research The diversity of sex development: What do conditions affecting sex development teach us about sexual diversity?
Conditions affecting sex development show that sexual diversity is a natural part of human variation.
research Sex Differences in Opioid-Mediated Effects: Role of Androgens
Men and women react differently to opioids, with hormones potentially influencing these differences.
research Lavenders, Their Phytochemical Properties, and Their Uses for Medical and Cosmetic Purposes
Lavender is widely used for its calming effects and in beauty products, but its medical effectiveness is not fully proven and not FDA-approved.
research Rethinking serotonin’s role in mental health
Serotonin's role in mental health is complex and not fully understood, affecting treatment effectiveness.
research 176 Characterising Neurotransmitter Signalling in Human Skin and Hair Follicles
Skin and hair cells release serotonin and histamine naturally, which could help improve skin health.
research Trazodone and chlorpromazine a proposal treatment for syndrome post-finasteride and syndrome of post-selective serotonin reuptake inhibitors (post-SSRI)
Trazodone and chlorpromazine may help treat sexual dysfunction caused by finasteride and SSRIs.
research Progesterone Pretreatment Enhances Serotonin-Stimulated BDNF Gene Expression in Rat C6 Glioma Cells Through Production of 5α-Reduced Neurosteroids
research Post-SSRI sexual dysfunction & other enduring sexual dysfunctions
SSRI antidepressants can cause long-lasting sexual problems.
research Neurosteroid influence on affective tone
Endogenous neurosteroids may set a baseline mood.
research Alopecia: A Less Known but Devastating Side Effect of Serotonin Reuptake Inhibitors
Stopping SSRIs can reverse hair loss in some patients.
research Repurposing Finasteride and Serotonin Reuptake Inhibitors as Novel Antimicrobials: A Dual-Action Approach to Target Bacterial and Fungal Pathogens
Duloxetine, escitalopram, and finasteride may be effective against bacteria and fungi.
research Neuroendocrine Pathways in Skin Health and Homeostasis: A Systematic Review
The skin communicates with the nervous system, and targeting neurohormones like melatonin and oxytocin could help treat skin issues.
research Antidepressant-like effect of fluoxetine may depend on translocator protein activity and pretest session duration in forced swimming test in mice
Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.
research Trazodone and chlorpromazine a proposal treatment for syndrome post-finasteride and syndrome of post-selective serotonin reuptake inhibitors (post-SSRI)
Trazodone and Chlorpromazine might help treat sexual dysfunction from finasteride and SSRIs.
research Alopecia associated with treatment with selective serotonin reuptake inhibitors (SSRIs)
SSRIs can cause hair loss, especially sertraline, with higher risk in women.
research O "25 de Abril" como ruptura sociobiográfica: potenciaçoes e refracçoes no campo cultural
Post-SSRI sexual dysfunction syndrome was formally recognized in 2006, impacting clinical practice and research.
research Melatonin-Loaded Nanoparticles for Enhanced Antidepressant Effects and HPA Hormone Modulation
Melatonin-loaded nanoparticles improve antidepressant effects and HPA hormone balance better than regular melatonin.
research Neurochemical and Immunocytochemical Studies of Catecholamine System in the Brindled Mouse
Brindled mice show abnormal catecholamine neuron development due to copper deficiency.
research PSSD,PFS,PRSD: A perspective for aetiology and treatment
The paper suggests that a decrease in estrogen receptor activity may cause sexual dysfunction syndromes and proposes hormonal treatments.
research TU55. EXPLORING THE GENOMIC RELATIONSHIP BETWEEN TWO MAJOR DETERMINANT PHENOTYPES OF PSYCHIATRIC DISORDERS: HUMAN GUT MICROBIOME AND SLEEP TRAITS
The research explores how gut bacteria and sleep patterns are related in mental health disorders.
research The neurosteroidogenic enzyme 5α-reductase modulates the role of D1 dopamine receptors in rat sensorimotor gating
5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.
research Characterizing enteric neurons in Dopamine Transporter (DAT)-Cre reporter mice reveals dopaminergic subtypes with dual-transmitter content
Dopaminergic neurons in the gut have distinct subtypes, some releasing both dopamine and acetylcholine.
research Reversible ageusia associated with losartan
Losartan can cause temporary loss of taste.