39 citations
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January 2019 in “The World Journal of Men's Health” Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
23 citations
,
August 2005 in “Expert opinion on pharmacotherapy” New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
18 citations
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October 2017 in “Drug Design Development and Therapy” DA-9401 helps protect rat testis from finasteride damage.
8 citations
,
July 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” DHT affects testicular development and regulates spermatogenesis in some fish.
7 citations
,
April 2015 in “General and Comparative Endocrinology” Finasteride negatively affects fish reproduction and gonadal development.
32 citations
,
July 2012 in “Stem Cells Translational Medicine” Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.
104 citations
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October 1999 in “The Journal of Urology” Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.
38 citations
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December 2010 in “Fertility and Sterility” Finasteride may cause male infertility, stopping it can help.
35 citations
,
April 2013 in “Sexual medicine reviews” 5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.
23 citations
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October 2015 in “Andrology” New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.
15 citations
,
October 2012 in “International Urology and Nephrology” Low-dose finasteride may cause fertility issues, but stopping it can improve sperm quality and lead to pregnancy.
9 citations
,
February 2020 in “International Journal of Endocrinology” Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.
9 citations
,
January 1997 in “Endocrine Journal” Gonadal biopsy is the best method to diagnose gonadal dysgenesis.
4 citations
,
October 2020 in “Toxicology Mechanisms and Methods” Hesperidin protects rat testicles from finasteride damage and improves sperm health.
3 citations
,
February 2018 in “Human Reproduction” A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.
2 citations
,
September 2017 in “Archives of Medical Science” Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.
1 citations
,
May 2025 in “The Journal of Phytopharmacology” Phytoandrogens from plants may help treat low testosterone naturally.
1 citations
,
December 2024 in “Bulletin of Osh State University” Mercury can disrupt sex hormones and cause reproductive issues.
April 2026 in “International Journal of Impotence Research” Anabolic steroid abuse can cause sexual, fertility, and health problems.
June 2025 in “Animal Bioscience” miRNA-24 affects goat coat color by controlling proteins involved in pigment production.
March 2025 in “Institutional Repositories DataBase (IRDB)” The testes significantly contribute to vitamin D metabolism and may affect male reproductive health and conditions like hair loss.
June 2024 in “Georgetown medical review” Finasteride treats hair loss but may cause low libido, erectile issues, and depression.
July 2022 in “International Journal of Health Sciences (IJHS) (En línea)” Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.
June 2021 in “Archives of Advances in Biosciences” Finasteride reduces sperm count and quality and alters hormone levels in mice.
25 citations
,
June 2012 in “Endocrine” PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.
228 citations
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January 2021 in “Journal of Neuroimmune Pharmacology” Men have more severe COVID-19 outcomes than women.
70 citations
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April 2014 in “Annales d'endocrinologie” New genes and pathways are important for testosterone production and male sexual development.
47 citations
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June 2016 in “JAMA Dermatology” Men with early hair loss have similar hormone levels to women with PCOS, possibly increasing risk of obesity and heart issues.
31 citations
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January 2014 in “Journal of endocrinological investigation” Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.
23 citations
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February 2021 in “Journal of Endocrinological Investigation” Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.