December 2023 in “International journal of molecular sciences” Chromosomal differences affect how muscle cells respond to testosterone.
June 2023 in “Journal of Liaquat University of Medical & Health Sciences” Higher PSA levels are linked to more hirsutism in women with PCOS.
October 2023 in “Frontiers in endocrinology” Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
December 2022 in “Urology Herald” Hormonal status from androgen deprivation therapy may affect COVID-19 severity in men.
November 2014 in “Elsevier eBooks” Gene mutations can cause problems in male genital development.
14 citations
,
May 2022 in “Frontiers in Endocrinology” Lower testosterone levels increase kidney stone risk in men over 40.
8 citations
,
May 1982 in “Journal of Endocrinology/Journal of endocrinology” Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
1 citations
,
August 2013 in “PubMed” Testosterone changes reduce thyroxin levels in rats.
December 2023 in “Biointerface Research in Applied Chemistry” Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.
122 citations
,
November 2014 in “BMC Medicine” Oral testosterone therapy raises heart risk more than other methods.
8 citations
,
March 2010 in “Gynecological Endocrinology” Free Testosterone Index, bioavailable testosterone, and androstenedione are the most accurate for diagnosing excess male hormones in PCOS.
4 citations
,
October 1988 in “Clinics in Dermatology” Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.
38 citations
,
July 1989 in “Archives of dermatological research” Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
16 citations
,
October 2007 in “Andrologia” DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
4 citations
,
March 2018 in “PloS one” Men with less sun-sensitive skin have lower PSA levels, while men with more sun-sensitive skin have higher PSA levels.
July 2022 in “International Journal of Health Sciences” Cardiac risk markers help assess heart risk in males with type 2 diabetes and low DHT.
January 2023 in “Iranian Journal of Pharmaceutical Research” Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.
3 citations
,
September 2016 in “Natural Product Communications” Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.
Androstenedione is better than testosterone for diagnosing PCOS in Indian women.
March 2022 in “VNU Journal of Science Medical and Pharmaceutical Sciences” A new method accurately measures nine steroid hormones in human serum with high sensitivity.
7 citations
,
August 2010 in “Medicinal Chemistry Research” Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.
5 citations
,
November 1999 in “Medical Hypotheses” Minoxidil, a common hair loss treatment, might work by counteracting a hormone that reduces hair growth and promotes hair loss.
6 citations
,
August 1996 in “The Journal of Clinical Endocrinology and Metabolism” MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
October 2010 in “Reproductive Biomedicine Online” Women with PCOS and androgenic alopecia have different triglyceride metabolism compared to those without hair loss.
118 citations
,
September 2004 in “Clinics in Dermatology” Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.
50 citations
,
March 2011 in “European Journal of Endocrinology” Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.
11 citations
,
March 1991 in “PubMed” Hormonal imbalances, including high prolactin and thyroid issues, contribute to hair growth problems in women.
75 citations
,
July 2013 in “The Journal of Clinical Endocrinology and Metabolism” Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.
36 citations
,
August 2011 in “Experimental Dermatology” Eccrine sweat gland's clear cells likely cause excessive sweating in hyperhidrosis.
22 citations
,
February 2008 in “Biochemical and Biophysical Research Communications” Androgen effects on hair follicles vary by skin area.