research P378: Expanding the phenotype of hyper-IgE syndrome: Heterozygous VUS in IL6ST with elevated serum IgE and isolated abscesses
A new IL6ST gene variant may cause a unique form of hyper-IgE syndrome with skin abscesses and high IgE levels.
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research Case Report: Successful Treatment of Alopecia Universalis With Tofacitinib and Increased Cytokine Levels: Normal Therapeutic Reaction or Danger Signal?
Tofacitinib regrew hair in a man with total hair loss but raised cytokine levels, needing more research on possible side effects.
research Alopecia Areata: A possible extraintestinal manifestation of Crohn's disease
Alopecia Areata might be linked to Crohn's disease.
research Some Trace Elements' Level in Alopecia Areata
Alopecia areata patients have lower zinc, copper, and selenium levels than healthy people.
research Ozenoxacin suppresses sebum production by inhibiting mTORC1 activation in differentiated hamster sebocytes
Ozenoxacin reduces sebum production, helping manage acne.
research Anti-androgenetic alopecia effect of policosanol from Chinese wax by regulating abnormal hormone levels to suppress premature hair follicle entry into the regression phase
Policosanol helps treat hair loss by balancing hormones and supporting hair growth.
research Positive Impact of Fish Oil on Diabetic and Hypercholestrolemic Skin Disorders
Fish oil improves skin health in people with diabetes and high cholesterol.
research Serum Levels of Transforming Growth Factor Beta1 (TGF β1) in Patients with Alopecia Areata.
People with severe Alopecia Areata have higher levels of TGF-β1, which may play a role in the condition.
research Ketoconazole Shampoo: Effect of Long-Term Use in Androgenic Alopecia
Ketoconazole shampoo improves hair growth and reduces oil similarly to minoxidil in male pattern hair loss.
research Sebum Free Fatty Acids Enhance the Innate Immune Defense of Human Sebocytes by Upregulating β-Defensin-2 Expression
Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.
research Pathways to inflammation: acne pathophysiology
Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
research Alarmin Cytokines as Central Regulators of Cutaneous Immunity
Alarmin cytokines are key in controlling skin immunity and inflammation.
research Influence of substance-P on cultured sebocytes
Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.
research An investigation of vitamin D status in alopecia areata
People with alopecia areata often have lower vitamin D levels and more inflammation, suggesting vitamin D might be involved in the condition.
research Oral tofacitinib: a promising treatment in atopic dermatitis, alopecia areata and vitiligo
Oral tofacitinib shows promise in treating atopic dermatitis and alopecia areata, but only slight improvement in vitiligo.
research Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 (RSK1) in a Growth- and Stress-dependent Fashion
Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.
research Endocrine evaluation of hirsutism
Women with excessive male-pattern hair growth should get a full hormone check-up to find and treat any underlying issues, considering both medical and emotional aspects.
research New substrates for stem cell control
New materials help control stem cell growth and specialization for medical applications.
research Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids
A new non-invasive method can analyze skin mRNA to understand skin diseases better.
research Genetically predicted levels of circulating cytokines and the risk of six immune skin diseases: a two-sample Mendelian randomization study
Certain cytokines may cause or be affected by immune skin diseases, suggesting possible new treatments.
research To evaluate the role of interleukin-6 in alopecia areata
Interleukin-6 may play a role in causing alopecia areata.
research Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women
The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.
research Serum adiponectin level is negatively related to insulin resistance in women with polycystic ovary syndrome
Lower adiponectin levels are linked to higher insulin resistance in women with PCOS.
research Systemic Circulating Leptin – Aiding New Dimension of Immune-Related Skin Carcinogenesis and Lipid Metabolism
High leptin levels may promote skin cancer and inflammation, suggesting potential for leptin-targeted therapies.
research Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids
The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.
research Exploring the effect of hsa-miR-19b-3p on IL-1R1 expression and serum levels in alopecia areata
Higher levels of IL-1R1 and hsa-miR-19b-3p may help diagnose and predict alopecia areata severity.
research Association between Vitamin D Deficiency and Psoriasis: A Case-Control Study
The study found no link between vitamin D deficiency and psoriasis but suggests more research is needed.
research Tissue Engineering of the Reproductive System
Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.
research A Comprehensive Review: The Bidirectional Role of Sebum in Skin Health
Sebum is essential for skin health but can cause acne if unbalanced.
research Evaluation of NF-κB as a Novel Serum Biomarker in Androgenetic Alopecia Patients: A Case–Control Study
NF-κB levels can help diagnose and assess the severity of androgenetic alopecia.