135 citations
,
March 1984 in “Fertility and sterility” Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.
December 2023 in “ANNALS OF ABBASI SHAHEED HOSPITAL AND KARACHI MEDICAL & DENTAL COLLEGE” Spexin levels are lower in PCOS patients and linked to metabolic and hormonal issues.
26 citations
,
August 2014 in “Genetic Testing and Molecular Biomarkers” High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.
60 citations
,
February 2010 in “Gynecological Endocrinology” Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.
3 citations
,
April 2019 in “Hormone and Metabolic Research” Women with PCOS have lower adiponectin hormone levels and are more likely to have insulin resistance.
February 2010 in “Journal of The American Academy of Dermatology” White hirsute women with PCOS have higher insulin resistance, but similar nitric oxide and fibrinogen levels compared to those with idiopathic hirsutism.
February 2020 in “Benha Journal of Applied Sciences” Higher Galectin-3 levels are linked to insulin resistance and may predict androgenetic alopecia severity.
44 citations
,
April 2008 in “The Journal of Clinical Endocrinology & Metabolism” Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.
2 citations
,
October 2024 in “Endocrine Connections” Lower adiponectin levels are linked to higher insulin resistance in women with PCOS.
December 2025 in “Frontiers in Endocrinology” High chromogranin A levels are linked to obesity and inflammation in polycystic ovary syndrome.
33 citations
,
September 2014 in “Reproductive Biology and Endocrinology” High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.
6 citations
,
May 2016 in “Urolithiasis” Balding and low testosterone increase risk of urinary stones.
38 citations
,
January 2011 in “Endocrine Journal” Weight loss and metformin don't significantly change vaspin levels in women with PCOS.
17 citations
,
May 2019 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.
7 citations
,
December 2014 in “Australasian journal of dermatology” Insulin resistance is not more common in idiopathic hirsutism patients than in healthy individuals.
March 2013 in “Journal of pediatric nursing” The case emphasizes the need for careful screening in children for insulin resistance and related conditions.
December 2021 in “Benha Journal of Applied Sciences” Higher Alarin levels may predict androgenetic alopecia and metabolic syndrome.
18 citations
,
May 2017 in “Fertility Research and Practice” Larger ovarian size is linked to higher insulin resistance in women with PCOS.
17 citations
,
December 2008 in “Dermatology” Taking metformin with intense-pulsed-light therapy improves hair removal for people with PCOS.
29 citations
,
March 2010 in “Journal of Endocrinological Investigation” Lipocalin-2 levels are higher in women with PCOS and may indicate insulin resistance.
6 citations
,
January 2018 in “Dermato-endocrinology” Darkened knuckles can be an early sign of insulin resistance.
16 citations
,
January 2012 in “European Journal of Endocrinology” The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.
10 citations
,
October 2014 in “Journal of Ovarian Research” The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.
August 2024 in “Archives of Women s Mental Health” Women with PCOS have more depression and stress due to high androgen levels, not obesity or insulin resistance.
1 citations
,
August 2023 in “South Asian Research Journal of Pharmaceutical Sciences” Fetuin A levels are higher in PCOS patients, while asprosin levels show no difference.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Hirsutism and acne indicate high androgen levels in women with PCOS, and early treatment can improve symptoms and quality of life.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Hirsutism and acne indicate high androgen levels in women with PCOS, suggesting early treatment can help.
24 citations
,
November 2015 in “Annals of Nutrition and Metabolism” Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.
February 2022 in “Mediators of Inflammation” Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.
26 citations
,
January 2000 in “Hormone research in paediatrics” Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.