August 2024 in “Australasian Journal of Dermatology” Australia needs better dermatological guidelines for gender-diverse patients.
July 2025 in “Indian Journal of Endocrinology and Metabolism” The guideline emphasizes a multidisciplinary approach and informed consent for gender-affirming hormone treatment, with regular follow-ups and individualized care.
75 citations
,
March 2023 in “JAMA Dermatology” Alopecia areata and its severe forms are becoming more common, especially among females, adults, and people in the Northeast.
1 citations
,
July 2024 in “Journal of Plastic Reconstructive & Aesthetic Surgery” Estrogen therapy can help stabilize the hairline in transfeminine individuals.
September 2025 in “Journal of Medical Case Reports” Finasteride is safe and effective for hair loss in transgender men, but may affect testosterone therapy.
10 citations
,
August 2022 in “Journal of clinical sleep medicine” Transgender youth have more sleep disorders, but gender-affirming therapy may help reduce them.
9 citations
,
April 2021 in “Annals of Translational Medicine” Facial contouring is crucial for the satisfaction and well-being of Chinese transgender females.
2 citations
,
June 2024 in “Plastic Surgery” There is unequal access to gender-affirming surgeries in Canada, with a need for better coverage and specialized programs.
March 2025 in “Journal of College of Physicians And Surgeons Pakistan” Many LGBTQ individuals in Lahore face skin issues, with androgenic alopecia, dry skin, and scabies being common, highlighting the need for better healthcare access and provider training.
3 citations
,
February 2021 in “JAMA Dermatology” Masculinizing hormone therapy increases the risk of hair loss in transgender and gender-diverse patients.
2 citations
,
December 2022 in “Journal of the American Academy of Dermatology” Hispanic/Latinx patients with alopecia areata often have it before age 40, with females and certain health conditions like rheumatoid arthritis more commonly affected.
1 citations
,
October 2022 in “Adolescent Health, Medicine and Therapeutics” Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.
March 2026 in “Journal of Dermatological Treatment” Topical 3% minoxidil effectively and safely enhances facial hair in transgender men.
1 citations
,
July 2025 in “BMC Psychology” Social rejection can harm long-term mental health in transgender individuals.
July 2024 in “Nursing Research” Hair and nail cortisol levels can show long-term stress in young males.
5 citations
,
December 2021 in “Pediatric investigation” Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.
2 citations
,
September 2022 in “Indian Journal of Dermatology, Venereology and Leprology” The transgender community in India has specific skin care needs and struggles to access dermatological services due to discrimination and financial issues.
2 citations
,
April 2021 in “PLoS ONE” Rural Bangladeshi girls mature later than peers in other low and middle-income countries due to poor nutrition and socioeconomic conditions.
May 2025 in “Neuropharmacology” Finasteride reduced seizures and prevented cognitive issues in rats after neonatal asphyxia but increased anxiety later.
January 2025 in “Case Reports in Genetics” A rare gene variant causes sexual development issues in siblings, needing personalized treatment.
May 2021 in “Journal of the Endocrine Society” Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.
March 2025 in “International Journal of Trichology” Dermatologists should address discrimination and consider ethnic and gender differences in treatments.
41 citations
,
July 2018 in “Frontiers in Neurology” Myotonic dystrophy may be classified as a segmental progeroid disorder.
19 citations
,
February 2021 in “Journal of Clinical Investigation” More research is needed on the health effects of hormone therapy for transgender and nonbinary people.
15 citations
,
September 2021 in “Frontiers in Endocrinology” Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.
5 citations
,
July 2022 in “Orphanet journal of rare diseases” RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
4 citations
,
July 2022 in “Clinical Cosmetic and Investigational Dermatology” Clascoterone 1% cream is a promising new treatment for acne.
3 citations
,
March 2024 in “iScience” Long-lived proteins may predict age-related diseases.
A balanced diet is crucial for normalizing hormone levels and managing obesity-related issues.
Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.