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Knee laxity varies with menstrual cycle phases, being highest during ovulation and menstruation, and is influenced by sex-steroids.

Men with early-onset baldness have a higher chance of heart disease and clogged arteries.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Women with low SHBG levels and a high 3a-diol G to SHBG ratio are likely to experience female pattern baldness, possibly due to a slight excess of androgens affecting sensitive hair bulbs.

Changes in SHBG levels don't predict diabetes risk reduction.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Testosterone helps human pancreatic cells increase insulin release.

Sex-limited chromosomes can affect traits not related to reproduction.

Sex hormones affect liver fat and metabolic health differently in men and women.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Male mice with FGF5 mutations grow longer hair than females.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

Both injectable contraceptives lower testosterone and SHBG levels, with NET-EN having a greater effect than DMPA-IM.

Sex and sex hormones can affect brain inflammation in Parkinson's disease, with male mice being more affected and female mice showing a protective effect.

Arab hair is generally thicker but less dense compared to other ethnicities, affecting hair disorder diagnosis and treatment.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

Following national healthy eating guidelines can help reduce risks from gender-affirming hormone therapy.

Creating evidence-based guidelines for gender incongruence is difficult due to the personalized nature of transgender medicine.

Conditions affecting sex development show that sexual diversity is a natural part of human variation.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Men generally have higher blood pressure than premenopausal women, but postmenopausal women's blood pressure can surpass men's, and hormone therapy doesn't significantly help.

A simple screening method found that 6.3% of women in a semiurban area in Sri Lanka have polycystic ovary syndrome, with most showing menstrual irregularities.

Women with PCOS and higher androgen levels are more likely to have fatty liver disease.