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Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

Sebocytes play a key role in controlling androgen levels in human skin.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

New genetic factors linked to acne risk were discovered, highlighting the role of certain pathways and genes.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

Combining antidiabetic drugs, hormonal therapies, and lifestyle changes can improve health in women with PCOS.

Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.

Puerariae Lobatae Radix can reduce sebaceous gland size and secretion, potentially treating related skin conditions.

People with advanced chronic kidney disease often have skin problems, which can be treated with various medications and procedures to improve their quality of life.

Genetic mutations can affect female sexual development, requiring personalized medical care.

The document concludes that hair analysis is not good for assessing nutrition but can detect long-term heavy metal exposure.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

De nouvelles thérapies promettent de mieux traiter la perte de cheveux due à l'alopécie androgénétique.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.

Mitotane changes steroid breakdown, affecting cortisol availability.

5α-reductase inhibitors may reduce male fertility and could be used for male contraception.

Exemestane may protect bones by stimulating osteoblast growth through androgen-related pathways.

Using 5-alpha reductase inhibitors may lower the risk of opioid addiction in men taking opioids.

Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.

5α-reductase inhibitors may cause persistent sexual dysfunction and depression, needing more research on long-term effects.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.