September 2022 in “Translational Andrology and Urology” Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.
November 2025 in “Frontiers in Psychiatry” People with androgenetic alopecia often experience more anxiety, depression, and lower self-esteem.
204 citations
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May 2014 in “The Journal of Sexual Medicine” Hormone therapy for trans individuals is effective and generally safe in the short term.
10 citations
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December 2008 in “Journal of Clinical Neuromuscular Disease” Finasteride can cause muscle pain and high creatine kinase levels, but stopping the medication may resolve symptoms.
March 2023 in “Translational Andrology and Urology” 5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.
2 citations
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October 2017 in “Drug safety - case reports” Finasteride for hair loss may cause painless bleeding in urine and semen.
7 citations
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January 2019 in “The Aging Male” Post-finasteride syndrome's existence is uncertain; more research needed.
March 2002 in “Clin-Alert” In 2002, various drugs caused serious side effects, including vitamin B12 deficiency, heart issues, blindness, hypersexuality, allergic reactions, blood clotting problems, pupil dilation, capillary leak syndrome, muscle breakdown, hepatitis, skin reactions, and lupus.
8 citations
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August 2021 in “Fertility and Sterility” Treatments for enlarged prostate can cause problems with ejaculation, and less invasive options might preserve sexual function better.
March 2025 in “Institutional Repositories DataBase (IRDB)” Hair cortisol can measure chronic stress but has inconsistent results.
March 2026 in “RS Global journals (RS Global Sp. z O.O.)” Finasteride is effective for hair loss and prostate issues but may cause lasting side effects.
February 2026 in “Frontiers in Endocrinology” Testosterone therapy improved symptoms in a woman with congenital adrenal hyperplasia.
October 2025 in “Asian Journal of Oral Health and Allied Sciences” Autologous growth factor concentrate therapy shows promise for treating early-stage hair loss safely and effectively.
Lupus severely affects daily life, work, and mental health, with many experiencing frequent flares and medication side-effects.
October 2007 in “Humana Press eBooks” Saw palmetto can help with prostate issues and may promote hair growth.
855 citations
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June 2009 in “The Journal of Clinical Endocrinology & Metabolism” The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.
January 2024 in “Wiadomości Lekarskie” Countries should improve sex education, access to contraception, and legal abortion options.
January 2023 in “Brazilian Journals Editora eBooks” The document concludes that Passiflora incarnata could help with anxiety, telemedicine might improve heart failure care, screen time for kids has increased, pregnant teens in Brazil are mostly okay with their body image, rare tuberculosis infection can occur after knee surgery, older and severely ill people are more likely to have long COVID-19 symptoms, HPLC might diagnose more diabetes cases, and psychiatrists should be involved in pain management.
The document concludes that current hair loss treatments have limitations and suggests researching new treatments targeting different factors of hair loss.
21 citations
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August 2016 in “Translational Andrology and Urology” Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.
99 citations
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June 1999 in “The Journal of Clinical Endocrinology and Metabolism” Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.
46 citations
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May 2009 in “Maturitas” Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.
5 citations
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January 2017 in “Laboratory Animal Research” Gold thread implantation may help hair grow in humans and mice.
5 citations
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March 2011 in “Journal of pediatric health care” The girl with autoimmune hair loss might regrow hair within a year, and treatments can help but not prevent recurrence; dermatologist referral and corticosteroids are recommended.
20 citations
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June 2015 in “Hormone Molecular Biology and Clinical Investigation” Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.
32 citations
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February 2014 in “Psychopharmacology” Dutasteride makes alcohol less sedating and may lead to less drinking in men.
3 citations
,
May 2016 in “Gynecological Endocrinology” Low-dose flutamide improved hirsutism and satisfaction in women but had common side effects, causing some to stop treatment.
May 1993 in “Drugs & Therapy Perspectives” Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.
55 citations
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March 2000 in “American journal of clinical dermatology” Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
20 citations
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December 1997 in “Clinical Endocrinology” Spironolactone may help reduce hair loss in androgenic alopecia.