research Identification and expression of the target gene SLC24A2 of oar-miR-377 and its novel SNPs effects on wool traits in sheep
The TT genotype of a specific SNP in sheep is linked to better wool quality.
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research 764 DNA dioxygenases Tet1/2/3 control hair matrix keratinocyte differentiation and hair shaft shape via regulation of hair keratin gene expression
The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.
research 1378 Identification of two distinct stem cell clusters, Lrig1-derived and Wnt/CD44-dependent, in corneal epithelium
The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.
research 1380 PPAR-γ modulation as a novel therapeutic strategy for scarring alopecia
A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.
research 1377 Decoding frontal fibrosing alopecia and lichen planopilaris: Macrophages hold the key?
Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.
research 1379 Cell of origin contributes to the melanoma diversity
Different types of stem cells in the skin contribute to the variety of melanoma forms.
research 1381 Molecular mechanisms of donor dominance in androgenetic alopecia
Hair pattern in androgenetic alopecia overlaps with scalp and bone demarcations, with distinct gene profiles affecting susceptibility.
research Multiple-wavelength radiation promotes hair growth by enhancing the early stages of hair follicle development in human dermal papilla cells and C57BL/6 mice
Multiple-wavelength radiation helps hair grow by boosting early hair follicle development.
research In vivo monitoring of hair cycle stages via bioluminescence imaging of hair follicle NG2 cells
Bioluminescence imaging can track hair follicle cells and help study hair regrowth.
research 947 Accelerating wound healing mechanisms with cold atmospheric plasma
Cold atmospheric plasma may speed up wound healing and control infections.
research 946 Therapeutic effect of combined platelet-rich plasma strategies on morphea
Combining platelet-rich plasma injections and gel may effectively treat morphea, improving skin elasticity and reducing pain.
research Drug discovery for alopecia: gone today, hair tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research Heparan Sulfate Regulates Hair Follicle and Sebaceous Gland Morphogenesis and Homeostasis
Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
research Tooth Regeneration: Insights from Tooth Development and Spatial-Temporal Control of Bioactive Drug Release
Tooth regeneration could become possible by controlling how and when bioactive factors are released.
research Growth factor mimetics for skin regeneration: In vitro profiling of primary human fibroblasts and keratinocytes
SUN11602 and ONO-1301 could help in skin healing and creating artificial skin.
research Embryologic layers in dermatology: Developmental checkpoint disorders, diagnostic insight, and regenerative futures
Understanding embryologic layers improves skin disorder diagnosis and supports developing targeted therapies.
research MicroRNA/mRNA regulatory networks in the control of skin development and regeneration
MicroRNAs are crucial for controlling skin development and healing by regulating genes.
research Skin transcriptome reveals the intrinsic molecular mechanisms underlying hair follicle cycling in Cashmere goats under natural and shortened photoperiod conditions
Changing light exposure can affect hair growth timing in goats, possibly due to a key gene, CSDC2.
research Roles of Wnt7a in embryo development, tissue homeostasis, and human diseases
Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
research Oil Body-Bound Oleosin-rhFGF-10: A Novel Drug Delivery System that Improves Skin Penetration to Accelerate Wound Healing and Hair Growth in Mice
A new drug delivery system using oil body-bound oleosin-rhFGF-10 improves wound healing and hair growth in mice.
research The overexpression of R-spondin 3 affects hair morphogenesis and hair development along with the formation and maturation of the hair follicle stem cells
Overexpression of R-spondin 3 leads to sparse hair and impaired hair regeneration.
research Transcriptional Control of Epidermal Stem Cells
Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
research Ectopic Sebaceous Glands in the Hair Follicle Matrix: Case Reports and Literature Review of this Embryogenic Anomaly
The cause and importance of misplaced oil glands in the hair follicle are not well understood.
research Diversity of Adult Stem Cell Niches in the Dermal Compartment of Skin
The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
research Smoothened receptor inhibitor vismodegib for the treatment of basal cell carcinoma: a retrospective analysis of efficacy and side effects
Vismodegib is effective for basal cell carcinoma but has severe side effects.
research Adverse events associated with vismodegib: insights from a real-world pharmacovigilance study using the FAERS database
Vismodegib can cause muscle spasms, taste changes, hair loss, fatigue, weight loss, and possibly new issues like skin cancer, dehydration, and swallowing problems, needing close monitoring.
research Evaluation of Animal Models Suitable for Hair Research and Regeneration
Animal models, especially mice, are essential for advancing hair loss research and treatment.
research Skin in the Game: Stem Cells in Repair, Cancer, and Homeostasis
Elaine Fuchs' research shows how skin stem cells maintain health, aid in healing, and are involved in cancer.
research Adenomatous Polyposis Coli (APC) Is Required for Normal Development of Skin and Thymus
The Apc gene is crucial for normal skin and thymus development.
research Management of Cutaneous and Extracutaneous Side Effects of Smoothened Inhibitor Therapy for Advanced Basal Cell Carcinoma
The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.