6 citations
,
September 2015 in “Journal of Investigative Dermatology” Using special RNA to target a mutant gene fixed hair problems in mice.
12 citations
,
January 2018 in “Journal of Drug Delivery Science and Technology” The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
39 citations
,
September 2012 in “Human Reproduction” Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.
Keratin peptides in hair may help identify gender and ethnicity, but more research is needed.
Encapsulating hair follicle cells in a special gel boosts their activity.
July 2024 in “International Journal of Molecular Sciences” The inhibitor DPP can promote hair growth.
September 2017 in “Journal of Investigative Dermatology” Hair follicle cells change their DNA packaging during growth cycles and when grown in the lab.
24 citations
,
May 2006 in “Proceedings of the National Academy of Sciences of the United States of America” Budesonide and N-acetylcysteine reduced tumors and alopecia in mice, regardless of FHIT gene status.
4 citations
,
September 2020 in “PeerJ” Platelet factor 4 slows down hair growth and could make hair loss treatments more effective if removed.
3 citations
,
January 2005 in “Biological & Pharmaceutical Bulletin” The peptide GPIGS helps hair cells grow and speeds up hair regrowth in mice.
43 citations
,
March 2009 in “Journal of Cellular and Molecular Medicine” TGF-β2 plays a key role in human hair growth and development.
January 2020 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” Polycomb Repressive Complex 1 is crucial for keeping stem cells stable and maintaining healthy adult tissues.
1 citations
,
January 2019 in “Annals of dermatology/Annals of Dermatology” STAT5 is crucial for hair growth in 3D cultured human dermal papilla cells.
April 2023 in “Journal of Investigative Dermatology” Skin cells and immune cells change in a skin condition called hidradenitis suppurativa, and a certain treatment can improve these changes.
September 2025 in “BMJ Case Reports” Platelet-rich plasma therapy may rarely trigger herpes zoster ophthalmicus.
7 citations
,
January 2023 in “Frontiers in cell and developmental biology” Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.
1 citations
,
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Polyamines are important in deciding hair follicle stem cell behavior, affecting hair growth and loss.
11 citations
,
January 2018 in “Acta dermato-venereologica” Researchers found specific genes in the part of hair follicles that could help treat hair disorders.
Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.
12 citations
,
April 2022 in “Journal of Bioscience and Bioengineering” Activating the PI3K/Akt pathway improves hair growth by human dermal papilla cells in hair beads.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.
38 citations
,
June 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” Peptide hydrogel scaffolds help grow new hair follicles using stem cells.
ETS2 is crucial in squamous cell carcinoma development and could be a therapeutic target.
January 2019 in “DSpace@MIT (Massachusetts Institute of Technology)” Higher PHGDH levels cause unusual melanin buildup in hair follicles.
28 citations
,
February 2007 in “Cancer Research” Blocking certain proteins in mouse skin can reduce and shrink skin tumors.
May 2025 in “American Journal of Veterinary Research” Photobiomodulation did not significantly improve hair density in dogs with alopecia X.
117 citations
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September 2003 in “Molecular & cellular proteomics” The technology can help diagnose and subtype autoimmune diseases by identifying specific autoantibodies.
7 citations
,
March 2020 in “PloS one” α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.
16 citations
,
March 2019 in “Experimental dermatology” Injury changes how hair follicle stem cells behave, depending on the hair growth stage.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” A girl with excessive hair growth had a genetic change on chromosome 17 that reduced the activity of two genes linked to hair growth.