138 citations
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June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
7 citations
,
November 1997 in “Reproduction Fertility and Development” Epidermal growth factor disrupts hair and gland formation in bandicoots.
2 citations
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May 2011 in “International Journal of Dermatology” A 12-year-old boy in rural south India had a rare skin condition causing hair loss and inability to sweat.
105 citations
,
February 2010 in “Endocrinology” The skin produces and responds to thyroid-stimulating hormone, which is controlled by other thyroid-related hormones.
November 2025 in “JPRAS Open” Age and diabetes are linked to larger trichilemmal cysts, while hypertension is linked to smaller ones.
5 citations
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March 2016 in “Experimental and molecular pathology” Mice with alopecia areata had wider lymphatic vessels in their skin.
147 citations
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September 2006 in “Developmental Cell” Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.
April 2021 in “Sri Lanka Journal of Diabetes Endocrinology and Metabolism” Giant pituitary macroadenomas causing Cushing disease are rare and may need extra treatment if surgery fails.
9 citations
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September 2012 in “Clinical Endocrinology” More than half of patients who had acromegaly surgery experienced hair loss, with varying degrees of recovery.
2 citations
,
January 2018 in “PubMed” The man's symptoms improved and the tumor shrank after treatment with cabergoline.
16 citations
,
April 1998 in “Journal of Investigative Dermatology” ACTH promotes hair growth in mink, but α-MSH does not.
9 citations
,
April 2006 in “Experimental and Clinical Endocrinology & Diabetes” A woman's small, unnoticed adrenal mass turned out to be a rare non-Hodgkin's lymphoma, treated successfully with surgery and therapy.
22 citations
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July 2012 in “International Journal of Trichology” Miniaturized hairs stay connected to muscle in alopecia areata, allowing possible regrowth, but not in androgenetic alopecia.
January 2023 in “Pediatric Endocrinology Diabetes and Metabolism” Isolated pubic hair in infants is usually harmless and resolves on its own.
2 citations
,
June 2012 in “American Journal of Dermatopathology” A rare neck cyst in a 47-year-old man showed diverse skin cell types and was not linked to HPV.
Thyroid disorders include hypothyroidism, causing fatigue and weight gain, and hyperthyroidism, causing weight loss and anxiety.
January 2019 in “Jui rinsho hifuka” A dog's skin and digestive problems improved after treatment for thyroid cancer.
January 2017 in “Enlighten: Publications (The University of Glasgow)” Activating β-catenin and inactivating PTEN cause follicular tumors, not papillomas, similar to those in Cowden’s Disease.
1 citations
,
May 2021 in “Problemy e̊ndokrinologii” Androgen levels can increase at any age, affecting symptoms like acne, hair loss, and prostate size.
1 citations
,
August 2022 in “International journal of biological and chemical sciences” Iodine-deficient diets and antithyroid substances affected rat growth and behavior, but most adapted with positive weight gain.
19 citations
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June 1997 in “The Journal of Clinical Endocrinology & Metabolism” The treatment successfully lowered testosterone levels and reduced symptoms.
15 citations
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May 2013 in “American Journal of Medical Genetics - Part A” People with X-linked hypohidrotic ectodermal dysplasia have no sweat ducts and less, thinner hair.
January 2025 in “Clinical and Experimental Optometry” Men with androgenetic alopecia may have more severe dry eye and meibomian gland dysfunction.
21 citations
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December 2015 in “Development Growth & Differentiation” DHT is crucial for urethral formation, and its disruption can affect masculinization and lead to hypospadias.
40 citations
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June 2009 in “Journal of Cutaneous Pathology” AGA patients have fewer hairs and smaller follicles; T:V ratio above 4:1 may indicate AGA.
November 2022 in “Journal of the Endocrine Society” Removing the ovarian tumor improved the woman's hormonal symptoms.
43 citations
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April 2010 in “Developmental Biology” Sebaceous glands can form new hair follicles when activated, but hair follicle bulges cannot.
September 1989 in “PubMed” Genetic response to androgens is key in female pattern baldness, not SHBG levels.
21 citations
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November 2022 in “Frontiers in immunology” Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
March 2025 in “American journal of biochemistry & biotechnology/American journal of biochemistry and biotechnology” Higher levels of certain hormones and lower levels of minerals may contribute to hair loss.