6 citations
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May 2016 in “Urolithiasis” Balding and low testosterone increase risk of urinary stones.
15 citations
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May 1989 in “PubMed” Psoriasis on the scalp causes smaller oil glands and thinner hair but doesn't lead to hair loss.
1 citations
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January 2004 in “Wieś Jutra” Finasteride reduces hair loss by blocking testosterone's effects on scalp cells.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
24 citations
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September 2002 in “Der Urologe” A stronger dual 5α-reductase inhibitor could improve treatment for benign prostatic hyperplasia by further reducing DHT levels.
5 citations
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June 1995 in “Comparative biochemistry and physiology. Part C. Comparative pharmacology and toxicology/Comparative biochemistry and physiology. C. Comparative pharmacology and toxicology” Removing mink's adrenal glands causes their summer fur to grow earlier.
Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.
5 citations
,
August 2018 in “Sexual Medicine Reviews” 5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
September 2009 in “European Urology Supplements” After prostate removal surgery, higher initial prostate size was linked to higher urethral PSA levels and more severe male pattern baldness.
15 citations
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October 2012 in “International Urology and Nephrology” Low-dose finasteride may cause fertility issues, but stopping it can improve sperm quality and lead to pregnancy.
January 2011 in “International Society of Hair Restoration Surgery” Finasteride may reduce body hair in men.
October 2017 in “The Journal of Urology” Finasteride reduces the need for prostate surgery but may increase the risk of depression and persistent sexual side effects.
36 citations
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September 2001 in “Journal of The European Academy of Dermatology and Venereology” Finasteride doesn't reduce sexual function in people with hair loss.
77 citations
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May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
July 2025 in “Journal of Investigative Dermatology” Miniaturized hair follicles in androgenetic alopecia show abnormal mitochondrial activity and damage.
August 2021 in “Asian Journal of Pharmaceutical and Clinical Research” Plant extracts in shampoo improved hair thickness and density in men with hair loss.
2 citations
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April 2007 in “Journal of Labelled Compounds and Radiopharmaceuticals” The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.
20 citations
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August 2010 in “The Journal of Urology” Ezetimibe effectively reduces prostate size in cases of benign prostatic hyperplasia.
April 2012 in “The Journal of Urology” Persistent ED in Propecia users is not due to abnormal blood flow.
75 citations
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January 2014 in “Korean Journal of Urology” 5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.
November 2005 in “The Journal of Urology” 1 citations
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November 2021 in “Ultrasonography” Ultrasound boosts finasteride's hair growth effects in mice.
1 citations
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November 2013 in “Asian Journal of Pharmaceutical and Clinical Research” Medicated oil from Martynia annua leaves and fruits helps prevent hair loss caused by testosterone in mice.
July 2025 in “Reproductive Biology” Finasteride use in male rats may harm their male offspring's liver function.
November 2022 in “Journal of the Endocrine Society” A rare ovarian tumor caused high testosterone and excess hair in a woman, which was resolved after tumor removal.
25 citations
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October 1993 in “American Journal of Physical Anthropology” Lower DHT levels lead to more body hair growth.
12 citations
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February 2003 in “European Urology Supplements” Dutasteride reduces DHT more effectively than finasteride.
3 citations
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January 1985 in “Acta Obstetricia Et Gynecologica Scandinavica” A rare ovarian tumor caused early puberty signs in a 1-year-old girl, but surgery reduced hormone levels.
4 citations
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January 2012 in “International Journal of Cardiology” Dihydrotestosterone (DHT) worsens heart enlargement, and blocking it may help prevent heart issues.