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research A systematic review on Drug Re-profiling/Re-Purposing

August 2022 in “IARS international research journal”

The document concludes that drug repurposing, which is reusing known medicines for new illnesses, can provide faster, cheaper treatment options for various serious diseases, including cancer, COVID-19, and rare diseases.

research The Non-Cosmetic Dermatological Use of Botulinum Neurotoxin

March 2022 in “IntechOpen eBooks”

Botulinum Neurotoxin-A can treat acne, oily skin, rosacea, hair loss, prevent scars, relieve nerve pain, reduce excessive sweating, and manage psoriasis, but more trials are needed to confirm its effectiveness.

research Genetic screening of non-classic CAH females with hyperandrogenemia identifies a novel CYP11B1 gene mutation

April 2016 in “Hormones”

A new mutation in the CYP11B1 gene was found in a woman with mild hyperandrogenemia, a rare cause of non-classic congenital adrenal hyperplasia.

Environmental Endocrine Disrupting Chemicals and Their Epigenetic Influence on Androgenetic Alopecia

research Cyberspace Chat

March 2012 in “Hair transplant forum international”

Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.

research Author Index

May 2005 in “Journal of the American Academy of Dermatology”

research Peptide-Based PROTACs: Transitioning from Static Paradigm to a Dynamic Landscape within Targeted Protein Degradation

March 2026 in “Bioconjugate Chemistry”

Peptide-based PROTACs show promise in targeting hard-to-treat proteins, especially for cancer therapy.

research Molecular Analysis of the ABCA4 Gene Mutations in Patients with Stargardt Disease Using Human Hair Follicles

10 citations , May 2020 in “International Journal of Molecular Sciences”

Hair follicles can be used to study gene mutations in Stargardt disease.

research Evaluation of Personalized Skincare Through in-silico Gene Interactive Networks and Cellular Responses to UVR and Oxidative Stress

11 citations , October 2022 in “Clinical Cosmetic and Investigational Dermatology”

Personalized skincare can be improved by understanding genetic differences and using compounds like Resveratrol and Quercetin.

In Silico Analysis of Gene Expression Data from Bald Frontal and Haired Occipital Scalp to Identify Candidate Genes in Male Androgenetic Alopecia

research In silico analysis of gene expression data from bald frontal and haired occipital scalp to identify candidate genes in male androgenetic alopecia

6 citations , September 2019 in “Archives of Dermatological Research”

Found 32 genes linked to male baldness, affecting hair growth and stress-related pathways.

research A Concept on The Development of The DRDE Series of Compounds for Skin Diseases Using In-Silico ADME And Drug-Likeness Analysis

March 2026 in “Preprints.org”

DRDE-07 shows promise for treating skin diseases due to its favorable properties.

research In‐silico</i> Screening of ATP‐competitive Inhibitory Activities of Phytochemicals against Janus Kinase 3 and Its In‐vitro* Evaluation*

April 2020 in “The FASEB journal”

Poncirin is a promising inhibitor of Janus Kinase 3, potentially better than tofacitinib.

research UHPLC-Q-Orbitrap HRMS-based Metabolomics and In Silico Studies on 5-α-Reductase, JAK1, JAK2, and JAK3 of Albizia saponaria L.: Application to Alopecia
March 2026 in “Tropical Journal of Natural Product Research”

Albizia saponaria bark extract may help treat hair loss.

research Reprogramming of Aged Dermal Papilla Cells in Vitro: In Silico Insight into the Biomarkers of Hair Growth and Tissue Repair
December 2025 in “Preprints.org”

Aging dermal papilla cells can be reprogrammed for potential hair growth and skin repair.

research Host-directed FDA-approved drugs with antiviral activity against SARS-CoV-2 identified by hierarchical in silico/in vitro screening methods
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Five FDA-approved drugs may help block COVID-19 virus entry.

research Exploring the Inhibitory Potential of Phytosterols β-Sitosterol, Stigmasterol, and Campesterol on 5-Alpha Reductase Activity in the Human Prostate: An In Vitro and In Silico Approach
12 citations , November 2024 in “Plants”

Phytosterols may help manage prostate issues but are less effective than synthetic drugs.

research Tuning Scaffold Properties of New 1,4-Substituted Pyrrolo[3,2-c]quinoline Derivatives Endowed with Anticancer Potential, New Biological and In Silico Insights
December 2025 in “Biomolecules”

Compound 7p shows strong potential as an anticancer agent.

research Evaluation of Phytochemicals and Anticancer Potential of C. maxima: An In-silico Molecular Docking Approach
December 2022 in “Journal of Natural Remedies”

Cucurbita maxima seed extract shows promise for breast cancer treatment.

research cis-Element- and Transcriptome-Based Screening of Root Hair-Specific Genes and Their Functional Characterization in Arabidopsis
188 citations , May 2009 in “Plant physiology”

Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.

research Clinical Snippets
July 2016 in “Experimental Dermatology”

New treatments for hair growth and psoriasis may be possible, and gene differences could affect baldness and the severity of skin conditions.

research Thyroid hormones and androgens differentially regulate gene expression in testes and ovaries of sexually mature Silurana tropicalis
13 citations , July 2018 in “General and comparative endocrinology”

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

research Clinical Snippets
July 2016 in “Journal of Investigative Dermatology”

R-spondin2 may help treat hair loss, gene differences could explain baldness, a peptide's regulation is linked to psoriasis, B-defensin gene copies may affect a skin condition's risk and severity, and potential markers and targets for alopecia areata were identified.

research Genome-wide gene expression dataset used to identify potential therapeutic targets in androgenetic alopecia
4 citations , May 2017 in “Data in Brief”

Five molecular elements identified as potential future targets for hair loss therapy.

research Glutamic acid promotes hair growth in mice
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Glutamic acid helps mice grow hair.

research 1430 Modeling the onset of senescence associated secretory phenotype predicts therapeutic targets
April 2018 in “Journal of Investigative Dermatology”

The research found that blocking a gene called NEMO can potentially prevent harmful effects of aging at the cellular level.

research Influence of functionalized silicones on hair fiber–fiber interactions and on the relationship with the macroscopic behavior of hair assembly
3 citations , March 2010 in “International Journal of Cosmetic Science”

Functionalized silicones improve hair appearance, combing, and manageability.

research Use of silicon for skin and hair care: an approach of chemical forms available and efficacy
45 citations , June 2016 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia”

Silicon can improve skin and hair health, but more research is needed.

research GC–MS profiling and in silico prediction of MAPK receptor activation by fatty acids of watercress oil for hair growth marketed in Saudi Arabia
5 citations , January 2021 in “Journal of Saudi Chemical Society”

Watercress oil may promote hair growth by activating specific receptors.

research In silico prediction of prostaglandin D2 synthase inhibitors from herbal constituents for the treatment of hair loss
30 citations , October 2015 in “Journal of Ethnopharmacology”

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

research In silico analysis of ethyl acetate Bruguiera gymnorhiza leaf extracts as an anti-inflammatory agent
4 citations , September 2024 in “Jurnal Pengolahan Hasil Perikanan Indonesia”

Bruguiera gymnorhiza leaf extracts show potential for developing anti-inflammatory drugs.

research In vivo and in silico</i> evaluation of the ameliorative effect of hesperidin on finasteride-induced testicular oxidative stress in Wistar rats
4 citations , October 2020 in “Toxicology Mechanisms and Methods”

Hesperidin protects rat testicles from finasteride damage and improves sperm health.

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Research

research A systematic review on Drug Re-profiling/Re-Purposing

research The Non-Cosmetic Dermatological Use of Botulinum Neurotoxin

research Genetic screening of non-classic CAH females with hyperandrogenemia identifies a novel CYP11B1 gene mutation

research Cyberspace Chat

research Author Index

research Peptide-Based PROTACs: Transitioning from Static Paradigm to a Dynamic Landscape within Targeted Protein Degradation

research Molecular Analysis of the ABCA4 Gene Mutations in Patients with Stargardt Disease Using Human Hair Follicles

research Evaluation of Personalized Skincare Through in-silico Gene Interactive Networks and Cellular Responses to UVR and Oxidative Stress

research In silico analysis of gene expression data from bald frontal and haired occipital scalp to identify candidate genes in male androgenetic alopecia

research A Concept on The Development of The DRDE Series of Compounds for Skin Diseases Using In-Silico ADME And Drug-Likeness Analysis

research In‐silico</i> Screening of ATP‐competitive Inhibitory Activities of Phytochemicals against Janus Kinase 3 and Its In‐vitro* Evaluation*

research UHPLC-Q-Orbitrap HRMS-based Metabolomics and In Silico Studies on 5-α-Reductase, JAK1, JAK2, and JAK3 of Albizia saponaria L.: Application to Alopecia

research Reprogramming of Aged Dermal Papilla Cells in Vitro: In Silico Insight into the Biomarkers of Hair Growth and Tissue Repair

research Host-directed FDA-approved drugs with antiviral activity against SARS-CoV-2 identified by hierarchical in silico/in vitro screening methods

research Exploring the Inhibitory Potential of Phytosterols β-Sitosterol, Stigmasterol, and Campesterol on 5-Alpha Reductase Activity in the Human Prostate: An In Vitro and In Silico Approach

research Tuning Scaffold Properties of New 1,4-Substituted Pyrrolo[3,2-c]quinoline Derivatives Endowed with Anticancer Potential, New Biological and In Silico Insights

research Evaluation of Phytochemicals and Anticancer Potential of C. maxima: An In-silico Molecular Docking Approach

research cis-Element- and Transcriptome-Based Screening of Root Hair-Specific Genes and Their Functional Characterization in Arabidopsis

research Clinical Snippets

research Thyroid hormones and androgens differentially regulate gene expression in testes and ovaries of sexually mature Silurana tropicalis

research Clinical Snippets

research Genome-wide gene expression dataset used to identify potential therapeutic targets in androgenetic alopecia

research Glutamic acid promotes hair growth in mice

research 1430 Modeling the onset of senescence associated secretory phenotype predicts therapeutic targets

research Influence of functionalized silicones on hair fiber–fiber interactions and on the relationship with the macroscopic behavior of hair assembly

research Use of silicon for skin and hair care: an approach of chemical forms available and efficacy

research GC–MS profiling and in silico prediction of MAPK receptor activation by fatty acids of watercress oil for hair growth marketed in Saudi Arabia

research In silico prediction of prostaglandin D2 synthase inhibitors from herbal constituents for the treatment of hair loss

research In silico analysis of ethyl acetate Bruguiera gymnorhiza leaf extracts as an anti-inflammatory agent

research In vivo and in silico</i> evaluation of the ameliorative effect of hesperidin on finasteride-induced testicular oxidative stress in Wistar rats