research An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice (Acomys)
A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.
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870-900 / 1000+ results research Multi-scale modeling for cell fate specification during regeneration and development
Signaling factors and gene-driven cell adhesion are crucial for wound healing and embryo development.
research Frontal fibrosing alopecia shows robust T helper 1 and Janus kinase 3 skewing
Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.
research Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response
Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.
research Enhancing diabetic wound healing: advances in electrospun scaffolds from pathogenesis to therapeutic applications
Electrospun scaffolds can improve healing in diabetic wounds.
research Phosphatase Regulator NIPP1 Restrains Chemokine-Driven Skin Inflammation
NIPP1 is important for healthy skin and could help treat skin inflammation.
research The role of activins and follistatins in skin and hair follicle development and function
Activins and follistatins, part of the TGFβ family, are crucial for hair follicle development and skin health, affecting growth, repair, and the hair cycle.
research The activin binding proteins follistatin and follistatin-related protein are differentially regulated in vitro and during cutaneous wound repair
FLRG and follistatin have different roles in wound healing.
research MORPHOLOGICAL CHARACTERISTICS OF ACELLULAR DERMAL MATRIX MANUFACTURING
The method effectively creates acellular dermal matrix from pig skin while preserving structure.
research Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis
FGFs-4, -8, and -9 have overlapping roles and are repeatedly used in tooth development.
research Effect of sinapic acid on hair growth promoting in human hair follicle dermal papilla cells via Akt activation
Sinapic acid may help hair growth by activating a specific cell pathway.
research Transplanted hair follicle stem cells migrate to the penumbra and express neural markers in a rat model of cerebral ischaemia/reperfusion
Hair follicle stem cells may help repair the brain after a stroke.
research Collagen-type synthesis in human-hair papilla cells in culture
research Stromal Vascular Fraction and Platelet-Rich Plasma Upregulate Vascular Endothelial Growth Factor Expression to Promote Hair Growth via the Wnt/β-Catenin Signaling Pathway
SVF and PRP promote hair growth by boosting specific proteins in the Wnt/β-catenin pathway.
research Clinicopathological characteristics of fibrosing alopecia in a pattern distribution: a single‐center, retrospective study
Younger people are at a higher risk for Fibrosing Alopecia in a Pattern Distribution than previously thought, with common symptoms and possible involvement of mast cells in its development.
research Investigating the mechanisms underlying age-related dysfunctions in skin and hair follicle regeneration
Senescence and genomic instability in fibroblasts contribute to hair loss and impaired skin regeneration with age.
research Homozygous missense mutation in theLIPHgene causing autosomal recessive hypotrichosis simplex in a Chinese patient
A specific gene mutation causes a rare hair loss condition in a Chinese patient.
research Formulation and Application of a Human Insulin-Like Growth Factor 1-Loaded Transfersomal System to Enhance Skin Wound Healing in Diabetic Rat Models
The system improved diabetic wound healing in rats.
research Preparation of Fucoidan-Based Electrospun Nanofibers and Their Interaction With Endothelial Cells
The nanofibers improved cell adhesion and could be used for tissue-engineered blood vessels.
research Effects of platelet-rich fibrin on repair and healing chronic refractory wounds in rats by regulating Wnt/b-catenin signalling pathway
Platelet-rich fibrin helps heal stubborn wounds in rats by reducing inflammation and boosting tissue repair.
research The Role of injectable platelet-rich fibrin(i-PRF) and Advanced platelet-rich fibrin(A-PRF) in Androgenetic Alopecia: A New Frontier in Hair Regeneration
i-PRF and A-PRF are promising treatments for hair regrowth in androgenetic alopecia.
research In vivo promoted growth of mice hair follicles by the controlled release of growth factors
Controlled release of growth factors in hydrogels improved hair growth in mice.
research QS8: Analysis of the Whole Transcriptome in Breast Cancer Patients Undergoing Radiotherapy and Breast Reconstruction
Radiation therapy in breast cancer patients changes gene expression related to DNA damage, fibroblast growth, and hair follicle development, which could help improve treatment for radiation-induced fibrosis.
research Injectable Biomimetic Gels for Biomedical Applications
Injectable biomimetic gels can help heal tissues and deliver drugs but need improvements in strength and delivery.
research Spatiotemporal immunomodulation by engineered hair follicle stem cell-derived nanovesicles enables scarless regeneration of infected wounds
Engineered nanovesicles from hair follicle stem cells enable scarless healing of infected wounds.
research [Expressions and effects of autophagy-related genes in bleomycin-induced skin fibrosis of mice].
Activating autophagy might reverse skin fibrosis.
research Particulate 3D Hydrogels of Silk Fibroin-Pluronic to Deliver Curcumin for Infection-Free Wound Healing
The hydrogel effectively heals wounds and fights bacteria.
research Repeal and Replace: Adipocyte Regeneration in Wound Repair
Skin wounds can create fat cells that help regenerate hair follicles, with BMP signaling playing a crucial role in this process.
research Expansion of Human Dermal Papilla Cells for Clinical Applications Using Human Platelet-rich Plasma as a Substitute for Fetal Bovine Serum
Human platelet-rich plasma is better than fetal bovine serum for growing cells that help hair regrow.
research Forsythiaside A Activates AMP-Activated Protein Kinase and Regulates Oxidative Stress via Nrf2 Signaling
Forsythiaside A helps protect cells and liver from damage by reducing oxidative stress and boosting antioxidants.