research Topical SCD-153, a 4-methyl itaconate prodrug, for the treatment of alopecia areata
SCD-153 shows promise as an effective topical treatment for alopecia areata.
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research miR-29 is an important driver of aging-related phenotypes
miR-29 is a key factor that accelerates aging.
research Global expression profile and global genome methylation signatures in male patients with androgenetic alopecia
Differences in gene expression and methylation patterns found in AGA patients suggest potential targets for future treatments.
research AI-driven biomaterial design: an intelligent closed loop from reverse design to biological response
AI improves biomaterial design by making it faster, cheaper, and more effective for personalized medicine.
research Biological effects of human placental extracts - variations in manufacturing methods and compositions
Placental extracts have antioxidant, anti-inflammatory, and immune-boosting effects, but their exact workings are unclear.
research The Potential Application of Exosomes as Therapeutic Agents, Carriers, and Biomarkers in Skin Diseases
Exosomes could revolutionize skin disease treatment and healing.
research TCM “medicine and food homology” in the management of post-COVID disorders
Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.
research Hdac1 and Hdac2 regulate the quiescent state and survival of hair-follicle mesenchymal niche
Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
research Minoxidil Regulates Aging-Like Phenotypes in Rat Cortical Astrocytes In Vitro
Minoxidil may help reduce aging effects in brain cells.
research Combination therapy profoundly improved skin flap survival by modulating KATP channels and nitric oxide
The combination of azelaic acid, minoxidil, and caffeine significantly increased the survival of skin flaps by affecting certain body channels and nitric oxide levels.
research Extraction of phenolic compounds and evaluation of the antioxidant and phenolic compounds of onion (Allium cepa L.)
Onions have compounds that reduce cancer risk and improve antioxidant activity.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research Common pathologic pathways: A single prescription dream?
The conclusion suggests that treatments targeting root causes of chronic diseases may be developed by focusing on gene expression and lifestyle factors.
research What “regenerative” means in aesthetic medicine: a narrative literature review attempting to demystify the core essence of regenerative aesthetics
Regenerative aesthetic medicine aims to restore tissue function, but needs more consistent evidence and standardized practices.
research Ca 2+ -mediated protein citrullination regulates proliferation in the regenerating and malignant CNS
Ca²⁺-mediated protein citrullination controls cell growth in the CNS and may help treat brain tumors.
research Regulatory T Cell Heterogeneity in the Steady State and Tumor
Regulatory T cells adapt to different environments to control inflammation and support tissue repair.
research The legacy of Bruce Ames and mitochondrial DNA mutagenicity: integrating oxidative stress, aging, and modern perspectives
Bruce Ames's work has greatly influenced research on genetics, aging, and health, inspiring ongoing studies on mitochondria and longevity.
research De Novo Design of Anti-Aging Peptides
New peptides can delay aging and improve cell function.
research Establishment and identification of immortalized sheep ovarian granulosa cells
A stable sheep ovarian cell line was created for studying reproduction and hormones.
research Assessment of Vitamin D Levels Among a Sample of Medical Laboratory Visitors in Misurata City and their Association with Seasonal Variations
Many people in Misurata City have low vitamin D, especially women and those aged 35-45, with levels dropping in winter and spring.
research Hair Dermal papilla maintain its hair inducing characteristics via autocrine exosomal miR-23a-3p
Hair growth is maintained by specific cell signals.
research Exploring the Causal Relationship Between Plasma Proteins and Obstructive Sleep Apnea: A Study Using Genome-Wide Mendelian Randomization, Single-Cell RNA Sequencing Analysis, and Network Pharmacology
Certain plasma proteins and genes are linked to obstructive sleep apnea, suggesting potential new treatments.
research Wasabi leaf extract changes the expression levels of cytokine related genes in dermal papilla cells, which identified by the whole transcriptome
Wasabi leaf extract affects gene expression in skin cells.
research Radyoterapinin Metastatik Meme Kanseri Hücrelerindeki Mitokondri İlişkili Yolaklar Üzerine Etkisi
Radiotherapy affects mitochondrial-related genes in metastatic breast cancer cells.
research АКТУАЛЬНІ АСПЕКТИ РЕПАРАТИВНОЇ РЕГЕНЕРАЦІЇ ШКІРИ: СУЧАСНИЙ ПОГЛЯД НА ПРОБЛЕМУ
Advancements in skin regeneration focus on stem cells, nanotechnology, and bioengineered skin to improve healing and reduce scarring.
research Beslenme ve Yeme Bozukluklarında Dermatolojik Belirtiler: Geleneksel bir Derleme
Eating disorders often cause skin issues, which can help in early diagnosis and treatment.
research HPLC Profiling and Insilco studies of Chochurus olitoris (Jute) Leave Fractions against Steroid 5α-Reductase 2 (SRD5α2)
Jute leaves may help reduce DHT levels, potentially aiding in conditions like hair loss and prostate issues.
research Pilose antler extracts promotes hair growth in androgenetic alopecia mice by activating hair follicle stem cells via the AKT and Wnt pathways
Pilose antler extracts help hair growth by activating hair follicle stem cells.
research Research advances of tissue-derived extracellular vesicles in cancers
Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.
research Plant elicitor Peptides regulate root hair development in Arabidopsis
Peps help Arabidopsis plants grow more root hairs by affecting specific genes and calcium signaling.