August 2015 in “Free Radical Biology and Medicine” Nrf2 helps protect skin from damage but too much can cause skin problems.
25 citations
,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
252 citations
,
January 2008 in “Trends in Endocrinology and Metabolism” Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
150 citations
,
April 2013 in “Dermato-endocrinology” Estrogen therapy can reduce skin aging but has cancer risks.
5 citations
,
June 2025 in “Advances in Therapy” Metformin may help treat various skin conditions and aid in wound healing and skin aging.
101 citations
,
August 2010 in “PLoS ONE” Selenoproteins are crucial for healthy skin and hair.
73 citations
,
January 2013 in “European journal of dermatology/EJD. European journal of dermatology” Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.
7 citations
,
March 2023 in “Antioxidants” Rosemary may help treat various skin conditions due to its antioxidant and anti-inflammatory properties.
August 2015 in “Free Radical Biology and Medicine” Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.
295 citations
,
March 2016 in “Life Sciences” Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.
55 citations
,
August 2015 in “AAPS PharmSciTech” The cream with orange peel and liquorice extracts may help reduce skin aging.
21 citations
,
November 2023 in “International Journal of Molecular Sciences” Melatonin helps reduce aging signs in human eyelid skin.
July 2026 in “Frontiers in Veterinary Science” Sodium hyaluronate and eggshell membrane improve Ragdoll cats' skin and coat health.
April 2018 in “Journal of Investigative Dermatology” Resveratrol activates the Nrf2 pathway in human skin, significantly increasing the production and distribution of the antioxidant glutathione.
506 citations
,
January 2012 in “Molecular and Cellular Endocrinology” Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
January 2025 in “Pharmaceuticals” Nanocarriers can improve antioxidant delivery to the skin but face safety and production challenges.
1 citations
,
May 2019 in “Frontiers in Pharmacology” The book provides detailed information on natural ingredients in beauty products and emphasizes the need for more human trials to confirm their effectiveness.
39 citations
,
June 2017 in “Journal of Applied Research on Medicinal and Aromatic Plants” Plant-based ingredients are effective and safe for modern skincare products.
84 citations
,
April 2013 in “Applied Microbiology and Biotechnology” Mannosylerythritol lipids are good for skin and hair care products.
46 citations
,
October 2025 in “Journal of Nanobiotechnology” Plant-derived nanovesicles show promise for treating skin issues like hair loss and aging.
27 citations
,
May 2016 in “Dermatologic Surgery” Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.
February 2026 in “Cosmetics” Fenugreek is a promising cosmetic ingredient for skin and hair care.
Tiny particles called extracellular vesicles show potential for improving skin health in cosmetics, but more research is needed to confirm their safety and effectiveness.
January 2023 in “Postępy Dermatologii i Alergologii” Azelaic acid treats acne, rosacea, and hyperpigmentation with minimal side effects.
45 citations
,
January 2020 in “Pharmaceutical Biology” Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.
July 2026 in “Discover Food” Rosemary may help manage aging-related health issues.
3 citations
,
September 2021 in “Journal of Food Science and Nutrition” Red Ginseng Extract helps hair grow and improves skin health by stimulating cell growth and enhancing the body's antioxidant defense system.
March 2024 in “International journal of molecular sciences” Zinc, copper, and iron are important for skin health and may help diagnose skin diseases.
November 2025 in “International Journal of Applied and Experimental Biology” Hemp shows promise for skincare and hair care due to its therapeutic properties, but standardization and clinical evidence are needed.
6 citations
,
January 2025 in “Molecules” Combining polymers and lipids may improve antioxidant delivery for wound healing, but practical challenges remain.