research Expression patterns of programmed cell death 4 protein in normal human skin and some representative skin lesions
Increasing PDCD4 protein may help prevent or treat some skin cancers.
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research Cell death as an architect of adult skin stem cell niches
Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
research Cell death in the skin
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Cell death in skin function, inflammation, and disease
Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
research 332 OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity
ILC1-like cells can cause alopecia areata by affecting hair follicles.
research Effects of Microwave-Assisted Opuntia humifusa Extract in Inhibiting the Impacts of Particulate Matter on Human Keratinocyte Skin Cell
Microwave-assisted Opuntia humifusa extract protects skin cells from pollution damage.
research Cell death by cornification
Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
research Pharmacological Activation of Thermo–Transient Receptor Potential Vanilloid 3 Channels Inhibits Hair Growth by Inducing Cell Death of Hair Follicle Outer Root Sheath
Activating TRPV3 channels stops hair growth by killing hair follicle cells.
research Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma
Lower SMAD2/3 activation predicts more severe skin cancer.
research Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation
Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
research Cell Density-Dependent Upregulation of PDCD4 in Keratinocytes and Its Implications for Epidermal Homeostasis and Repair
PDCD4 is important for controlling skin cell growth and healing.
research Autophagy-Mediated Cellular Remodeling during Terminal Differentiation of Keratinocytes in the Epidermis and Skin Appendages
Autophagy is essential for proper skin cell development and function.
research BMP signaling in the control of skin development and hair follicle growth
BMP signaling is crucial for skin and hair growth.
research Apoptosis in Hair and Skin: A Review
The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.
research Persistently curly hair phenotype with the use of nivolumab for squamous cell lung cancer
A cancer patient's hair became permanently curly after treatment with nivolumab.
research Ligand-Independent Vitamin D Receptor Actions Essential for Keratinocyte Homeostasis in the Skin
Vitamin D receptor actions without binding are crucial for healthy skin and hair.
research What is it about your skin cancer that bothers you the most? 700 patients respond
Patients with nonmelanoma skin cancers are most bothered by fear of progression, appearance concerns, and having cancer.
research Mitochondrial Function in Murine Skin Epithelium Is Crucial for Hair Follicle Morphogenesis and Epithelial–Mesenchymal Interactions
Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.
research Accelerated senescence in skin in a murine model of radiation-induced multi-organ injury
High-dose radiation speeds up aging in skin stem cells.
research Apoptosis in human skin development: Morphogenesis, periderm, and stem cells
Apoptosis is essential for human skin development and forming a functional epidermis.
research Direct cellular reprogramming enables development of viral T antigen–driven Merkel cell carcinoma in mice
Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.
research 910 Transepidermal UV radiation of human scalp skin induces distinctive hair follicle damage, which is mitigated by topical caffeine treatment
Caffeine can protect scalp hair follicles from damage caused by UV radiation.
research Wwox Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin
WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
research Recent advances in understanding of radiation-induced skin tissue reactions with respect to acute tissue injury and late adverse effect
Understanding skin reactions to radiation has improved, helping to reduce injuries and prevent skin cancer.
research Study on the mechanism of cadmium chloride pollution accelerating skin tissue metabolism disorder, aging and inhibiting hair regeneration
Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.
research Temporal Dynamics of Endothelium After Radiation Injury Reveal a Transient Pro-Angiogenic Capillary Subpopulation Associated with Skin Repair
A temporary capillary cell type helps skin repair after radiation by promoting blood vessel growth.
research The orchestrated network of skin photoaging: From intercellular crosstalk to molecular signaling
UV radiation causes skin aging by damaging cells and triggering harmful processes.
research Molecular heterogeneity of quiescent melanocyte stem cells revealed by single-cell RNA-sequencing
Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.
research Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice
15-lipoxygenase helps keep skin healthy by reducing inflammation.
research Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells
Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.