19 citations
,
January 2017 in “Stem Cells International” Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.
17 citations
,
May 2021 in “Journal of Cell Science” N1-acetylspermidine promotes hair follicle stem cell self-renewal.
12 citations
,
February 2025 in “Scientific Reports” MSC-EVs and UCB-EVs improve skin wound healing and reduce scarring.
10 citations
,
June 2016 in “Wound Repair and Regeneration” The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.
6 citations
,
May 2021 in “Stem Cell Reviews and Reports” Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.
5 citations
,
June 2024 in “Free Radical Biology and Medicine” Maintaining natural oxygen levels is crucial for healthy skin cells and effective treatments.
5 citations
,
December 2017 in “Tissue and cell/Tissue & cell” Researchers found stem cells in dog hair follicles using specific markers.
5 citations
,
August 2013 in “InTech eBooks” KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
4 citations
,
January 2015 in “Hair therapy & transplantation” Hair follicle stem cells could be used to treat the skin condition vitiligo.
3 citations
,
July 2020 in “International Journal of Molecular Sciences” SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.
3 citations
,
April 2019 in “Stem cells international” Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.
2 citations
,
November 2025 in “Cells” Adipose-derived stem cell secretome is a promising and effective treatment for skin repair.
2 citations
,
November 2015 in “Actas Dermo-Sifiliográficas” Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.
1 citations
,
December 2015 in “Journal of the Medical Sciences (Berkala Ilmu Kedokteran)” Transplanting melanocyte stem cells from hair follicles can effectively treat vitiligo.
March 2026 in “Preprints.org” The combined stem cell secretome in the skin care product effectively reduces inflammation and promotes tissue regeneration.
New insights into cell communication in psoriasis suggest innovative drug treatments.
April 2016 in “Journal of Investigative Dermatology” Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
May 2014 in “Journal of Investigative Dermatology” Scientists developed tools to observe hair regeneration in real time and assess skin health, using glowing mice and light-controlled genes.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
124 citations
,
June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
97 citations
,
May 2019 in “Frontiers in Cell and Developmental Biology” Abnormal ECM and immune cell interactions can cause skin diseases.
83 citations
,
January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
49 citations
,
March 2019 in “Journal of Investigative Dermatology” Skin fat plays a key role in immune defense and healing beyond just storing energy.
42 citations
,
May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
6 citations
,
January 2017 in “Advances in Experimental Medicine and Biology” Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
610 citations
,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
Advances in RNA research and skin models offer hope for better skin healing without scarring.
351 citations
,
February 2010 in “Nature Cell Biology” Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
151 citations
,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
56 citations
,
March 2015 in “Cell death and differentiation” Older skin has higher cancer risk due to inflammation and stem cell issues.