77 citations
,
April 2016 in “Science Advances” Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
14 citations
,
July 2022 in “Applied Sciences” Extracellular vesicles can help repair and regenerate tissues with less risk of rejection.
July 2025 in “Journal of Investigative Dermatology” Wnt signaling helps regenerate hair follicles in wounds by reducing skin cell sensitivity to mechanical stress.
1 citations
,
January 2016 in “Elsevier eBooks” The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.
24 citations
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September 2002 in “Dermatologic Surgery” The study found that hair follicles are above muscle connections in the scalp, which may help protect stem cell areas.
11 citations
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April 2022 in “International Journal of Molecular Sciences” Understanding the Wnt/β-catenin pathway and photobiomodulation could improve diabetic wound healing.
7 citations
,
February 2015 in “Journal of comparative pathology” CD8+ T cells play a key role in graft-versus-host disease in certain mice models.
November 2024 in “International Journal of Cosmetic Science” Botanical extracts can improve scalp health by reducing oxidative stress.
January 2023 in “Research Square (Research Square)” IGF2BP3 gene is up-regulated in keloid patients, suggesting potential targets for treatment.
June 2026 in “Advanced Science” New cryomicroneedles can improve hair growth and regeneration.
Thymosin β4 helps with healing, inflammation, and organ protection.
95 citations
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February 2018 in “Dermatology and Therapy” Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.
31 citations
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August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
8 citations
,
June 2024 in “Pharmaceutics” PEA-ENL improves skin delivery and reduces inflammation without side effects.
115 citations
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December 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
January 2025 in “Cosmetics” Exosomes could help treat skin and hair issues by improving healing and reducing stress.
299 citations
,
January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
67 citations
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January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
14 citations
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June 2017 in “Immunity” Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.
1 citations
,
April 2023 in “Biomaterials advances” Gellan gum hydrogels help recreate the environment needed for hair growth cell function.
January 2013 in “Cahiers Pedagogiques” Calorie restriction boosts stem cell activity, improving tissue regeneration and lifespan.
161 citations
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August 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
28 citations
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August 2018 in “BMC genomics” DNA methylation changes are linked to hair growth cycles in goats.
18 citations
,
April 2016 in “The journal of immunology/The Journal of immunology” Thymic mesenchymal cells have unique gene expression that supports their specific functions in the thymus.
July 2023 in “Biomolecules” The circadian clock plays a key role in hair growth and its disruption can affect hair regeneration.
86 citations
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June 1998 in “Journal of Investigative Dermatology” The hairless gene mutation causes baldness by disrupting hair follicle structure.
37 citations
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April 2010 in “FEBS Letters” The study concludes that the EDA2R gene is activated by p53 during chemotherapy but is not necessary for chemotherapy-induced hair loss.
6 citations
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October 1989 in “PubMed” Optimized conditions and specific treatments enhance the growth of hair cells from C3H mice.
December 2024 in “Molecules” Bovine milk-derived exosomes may improve skin, hair, gut, brain, and bone health.
April 2017 in “Journal of Investigative Dermatology” Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.