24 citations
,
January 2019 in “Biomaterials Science” The shape of fibrous scaffolds can improve how stem cells help heal skin.
9 citations
,
February 2021 in “Frontiers in Cell and Developmental Biology” Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
8 citations
,
October 2018 in “Journal of the European Academy of Dermatology and Venereology” Mohs micrographic surgery is effective for early-stage non-melanoma skin cancers on the lips, with basal cell carcinoma more common on the upper cutaneous lip and squamous cell carcinoma more common on the lower vermilion lip.
4 citations
,
March 2013 in “InTech eBooks” Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
1 citations
,
November 2014 in “Elsevier eBooks” Future research should focus on making bioengineered skin that completely restores all skin functions.
June 2024 in “Regenerative Therapy” Exosomes from stem cells may help rejuvenate skin and regrow hair, but more research is needed.
822 citations
,
January 2021 in “Genome biology” scMC effectively separates biological signals from technical noise in single-cell genomics data.
401 citations
,
January 2013 in “Postepy Dermatologii I Alergologii” The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
375 citations
,
June 2013 in “Biochimica et biophysica acta. Molecular cell research” Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
265 citations
,
July 2012 in “Cell” The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.
205 citations
,
April 2005 in “Journal of Investigative Dermatology” Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
182 citations
,
May 2003 in “Development” Myc activation reduces skin stem cells by affecting cell adhesion.
156 citations
,
March 2022 in “Exploration” Bioactive inorganic particles-based biomaterials show promise for improving skin wound healing.
148 citations
,
May 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
68 citations
,
September 2018 in “International Journal of Molecular Sciences” Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.
60 citations
,
January 2015 in “World Journal of Stem Cells” Stem cells and biomaterials are key to improving skin substitutes for medical use.
54 citations
,
May 2021 in “International Journal of Molecular Sciences” Advances in mechanobiology and immunology could lead to scarless wound healing.
52 citations
,
May 2015 in “PLOS Genetics” miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.
50 citations
,
May 2019 in “BioFactors” Pollution increases a compound in the skin that can lead to faster aging and more inflammation.
44 citations
,
January 2019 in “Journal of Translational Medicine” Macrophages are essential for successful skin growth in reconstructive surgery.
42 citations
,
October 2006 in “Theriogenology” Porcine skin cells are useful for studying wound healing and cancer.
40 citations
,
August 2018 in “Disease Models & Mechanisms” Mature cells can re-enter the cell cycle and potentially lead to cancer.
36 citations
,
July 2014 in “Experimental Dermatology” Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.
36 citations
,
March 2009 in “Molecular Carcinogenesis” Disrupting Bcl-xL in mice reduces skin cancer risk.
34 citations
,
July 2009 in “Journal of Cell Science” ΔNp63α helps control a protein that stops cancer cells from spreading.
31 citations
,
January 2011 in “Journal of Biomaterials and Nanobiotechnology” Biodegradable polysaccharide gels can improve skin healing and reduce scarring.
29 citations
,
December 2016 in “The EMBO Journal” Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
28 citations
,
January 2023 in “Cell Transplantation” Nanofat with stem cells is promising for treating hair loss, scars, and skin rejuvenation.
28 citations
,
February 2014 in “PLoS ONE” Epidermal stem cells on a special membrane helped mice regrow full skin with hair and functions.
27 citations
,
July 2020 in “Stem Cells International” ADSC therapy is more effective and safer for treating photoaged skin than PRP.