research Keratinization and its Disorders
Mutations in keratin genes can cause skin and mucosa disorders.
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research Control of hair follicle cell fate by underlying mesenchyme through a CSL–Wnt5a–FoxN1 regulatory axis
Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
research N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting
Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
research Edar Signaling in the Control of Hair Follicle Development
Edar signaling is crucial for proper hair follicle development and function.
research Alarmin Cytokines as Central Regulators of Cutaneous Immunity
Alarmin cytokines are key in controlling skin immunity and inflammation.
research Cutaneous applied nano-ZnO reduce the ability of hair follicle stem cells to differentiate
Nano-ZnO on skin may hinder hair growth by affecting stem cells.
research Insight into Reepithelialization: How Do Mesenchymal Stem Cells Perform?
Mesenchymal stem cells help improve wound healing by reducing inflammation and promoting skin cell growth and movement.
research The Dynamic Duo: Niche/Stem Cell Interdependency
Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.
research Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity
Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
research Equine Epidermis: A Source of Epithelial-Like Stem/Progenitor Cells with In Vitro and In Vivo Regenerative Capacities
Horse skin stem cells combined with platelet-rich plasma improve skin healing.
research Cutaneous stem cells: something new and something borrowed
Epidermal stem cells maintain skin health through specific niches and signaling pathways.
research Human Macrophages Preferentially Infiltrate the Superficial Adipose Tissue
Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.
research Epidermis reconstructed from the outer root sheath of human hair follicle. Effect of retinoic acid
Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor α Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research Establishment of a new three‐dimensional human epidermal model reconstructed from plucked hair follicle‐derived keratinocytes
A new skin model from hair follicles is a safer, simpler alternative for skin tests.
research Extracellular Vesicles: Emerging Therapeutics in Cutaneous Lesions
Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.
research Epidermal stem cells: an update on their potential in regenerative medicine
Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
research Utility of platelet-rich plasma in aesthetics
PRP is popular in aesthetic treatments but its effectiveness and safety are still questioned.
research Epigenetic orchestration of RNA m6A methylation in wound healing and post-wound events
m6A methylation is crucial for proper wound healing and tissue repair.
research Ptch2 is a Potential Regulator of Mesenchymal Stem Cells
Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.
research 516 Intrinsic factors regulating hair growth: insights into growth factors, cytokines, chemokines, and interferons
Red ginseng components help prevent skin aging by reducing inflammation and improving cell function.
research ALOPECIA AREATA PROFILING SHOWS LNCRNAS REGULATE THE SUPPRESSED EXPRESSION OF KERATIN.
Certain RNAs may help diagnose alopecia areata by affecting keratin genes.
research Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation
Key skin cell regulators and gene organization changes are crucial for skin cell development and could help treat skin disorders.
research Transcriptomic landscape of early hair follicle and epidermal development
Researchers identified new cell types and genes in early hair follicle development.
research Hair Growth Promoting Effect of Radish Crude Saponin Extract on Athymic Nude Mice
Radish saponin extract may help grow hair in balding mice.
research Cutaneous applied nano-ZnO reduce the ability of hair follicle stem cells to differentiate
Nano-Zinc oxide on skin reduces hair follicle stem cell differentiation.
research LB788 Development of a novel three-dimensional human epidermal model from plucked hair follicle-derived keratinocytes
Scientists created a new 3D skin model from cells of plucked hairs that works like real skin and is easier to get.
research Cutaneous Epithelial Stem Cells
Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
research UTX (KDM6A) promotes differentiation noncatalytically in somatic self-renewing epithelia
UTX is crucial for skin differentiation and health, especially in females.
research INVESTIGATIONS INTO THE ROLE OF THE X-LINKED EPIGENETIC REGULATOR UTX (KDM6A) IN SELF-RENEWING STRATIFYING EPITHELIA
UTX is important for skin health and its loss can lead to skin issues, especially in females.