82 citations
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May 2009 in “Development” EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
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January 2016 in “Stem Cells International” Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Ezh2 controls skin development by balancing signals for dermal and epidermal growth.
January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
6 citations
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June 2021 in “Developmental biology” Dermal EZH2 controls skin cell development and hair growth in mice.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Dermal EZH2 controls skin cell growth and differentiation in mice.
January 2014 in “Durham e-Theses (Durham University)” Notch1 helps skin heal by attracting cells that aid repair.
April 2016 in “Journal of Investigative Dermatology” Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
4 citations
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March 2017 in “Development” Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
Aging disrupts skin repair and stress responses, but exercise-related IL-15 improves wound healing and skin health in older skin.
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January 2021 CD4+ skin cells may be precursors to basal cell carcinoma.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
132 citations
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January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
35 citations
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July 2022 in “Frontiers in Cell and Developmental Biology” Proper mTOR signaling is crucial for healthy skin and preventing skin diseases.
120 citations
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August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
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January 2022 in “Theranostics” Collagen XVII is important for skin aging and wound healing.
December 2025 in “The Journal of Cell Biology” Keratin 15 helps maintain skin cell growth and repair.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
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August 2022 in “Nature communications” A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.
253 citations
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March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
211 citations
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May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
201 citations
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May 2001 in “Proceedings of the National Academy of Sciences” Overexpression of COX-2 in mice skin causes abnormal skin and hair development.
153 citations
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October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
133 citations
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September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
15 citations
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December 2020 in “International journal of molecular sciences” Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.
14 citations
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May 2022 in “Stem cell reports” The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
August 2018 in “Journal of Investigative Dermatology” The conclusion is that using light-sheet fluorescence microscopy with a special solution can effectively create detailed 3D images of human skin for dermatological research.
19 citations
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August 2024 in “Journal of Translational Medicine” Epidermal stem cells are vital for skin healing and have potential for treating skin disorders.
55 citations
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March 2012 in “Journal of Investigative Dermatology” Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
28 citations
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April 1996 in “Cell biology international” Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.