84 citations
,
October 2014 in “PLoS Genetics” Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.
9 citations
,
March 2019 in “Molecular & cellular proteomics” Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.
106 citations
,
October 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
103 citations
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November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
April 2018 in “Journal of Investigative Dermatology” Fetuin A, Anigozanthos Flavidus extract, and Ovol2 affect wound healing and skin regeneration.
72 citations
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July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
24 citations
,
March 2022 in “Stem Cell Research & Therapy” Dendritic epidermal T cells help wounds heal faster by boosting skin stem cell growth.
76 citations
,
February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
46 citations
,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
10 citations
,
September 2018 in “Regenerative Medicine” New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
August 2023 in “Research Square (Research Square)” Two microRNAs affect hair follicle development in sheep by targeting specific genes.
260 citations
,
December 2012 in “Cold Spring Harbor Perspectives in Biology” Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
28 citations
,
April 1996 in “Cell biology international” Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
9 citations
,
June 2019 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” A specific RNA increases hair stem cell growth and skin healing by affecting a protein through interaction with a microRNA.
6 citations
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November 2018 in “Histochemistry and Cell Biology” Mongolian gerbils heal wounds differently than mice, with unique protein levels and gene expression that affect skin repair.
March 2026 in “Frontiers in Cell and Developmental Biology” Vascular endothelial cells may significantly influence skin stem cells, but more research is needed.
July 2025 in “Archives of Toxicology” The new skin model can predict how chemicals might cause skin allergies.
September 2017 in “Journal of Investigative Dermatology” Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.
72 citations
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April 2008 in “Organogenesis” Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
12 citations
,
September 2018 in “Naturwissenschaften” Melatonin treatment increases a specific RNA in goat cells that boosts cashmere growth.
4 citations
,
October 2022 in “Frontiers in public health” Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.
2 citations
,
October 2025 in “Journal of Materials Science Materials in Medicine” The composite speeds up skin healing and is safe for use in wound dressings.
April 2019 in “Journal of Investigative Dermatology” New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.
176 citations
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January 2003 in “Journal of Investigative Dermatology” Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
174 citations
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April 2005 in “The American journal of pathology (Print)” Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.
133 citations
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September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
112 citations
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May 2020 in “Nature Communications” Adult fibroblasts help heart cells mature and improve heart function.
86 citations
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April 2016 in “Nature Communications” Notch1 helps skin heal by attracting specific immune cells.
39 citations
,
August 2022 in “Cell Death and Disease” DA-MeHA hydrogel effectively aids stem cell-based skin regeneration.
35 citations
,
April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.