research Bioengineering Skin Constructs
Future research should focus on making bioengineered skin that completely restores all skin functions.
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research A regenerative stem cell-derived matrix accelerates functional dermal wound repair in a preclinical diabetic model
A stem cell-derived matrix speeds up healing of diabetic skin wounds.
research Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell–Derived Skin Organoids to Inflammation and Injury
Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
research Understanding Type 3 Innate Lymphoid Cells and Crosstalk with the Microbiota: A Skin Connection
Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.
research Molecular heterogeneity of quiescent melanocyte stem cells revealed by single-cell RNA-sequencing
Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.
research Mapping Human Skin: One Sequenced Cell at a Time
The article concludes that creating a detailed map of normal human skin at the single-cell level is important.
research Histological Study on the Effect of Hyaluronic Acid Injection (Dermal Filler) on the Skin of the Adult and Aged Albino Rat
Hyaluronic acid injections improve skin thickness and quality, protecting against aging in rats.
research Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth
Growing human skin cells in a 3D environment can stimulate new hair growth.
research Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins
Skin-derived precursors in hair follicles come from different origins but function similarly.
research Concise Review: Tissue-Engineered Skin and Nerve Regeneration in Burn Treatment
New methods for skin and nerve regeneration can improve healing and feeling after burns.
research Generation and characterization of hair-bearing skin organoids from human pluripotent stem cells
Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
research Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice
15-lipoxygenase helps keep skin healthy by reducing inflammation.
research The melanocyte photosensory system in the human skin
Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.
research Sebaceous Gland Regeneration in Human Skin Xenografts
Human sebaceous glands can grow back in skin grafts on mice and work like normal human glands.
research Ancestral Diversity of Skin Reaches Single-Cell Resolution
Ancestry affects skin healing, with non-Hispanic Black patients showing more healing-related fibroblasts than White patients.
research Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis
A specific group of immune and skin cells may cause chronic inflammation in atopic dermatitis.
research Wound Healing and Skin Regeneration
Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
research Nascent blood vessels in the skin arise from nestin-expressing hair-follicle cells
Hair follicle cells can create new blood vessels in the skin.
research dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration
Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
research Dermal papilla-induced hair differentiation of adult epithelial stem cells from human skin
Dermal papilla cells help skin stem cells grow into hair.
research Chapter 6 Fetal Skin Wound Healing
Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
research Autologous Cellular Method Using Micrografts of Human Adipose Tissue Derived Follicle Stem Cells in Androgenic Alopecia
Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.
research Regeneration of skin appendages and nerves: current status and further challenges
Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
research Next generation human skin constructs as advanced tools for drug development
Advanced human skin models improve drug development and could replace animal testing.
research Progenitor Cell Dysfunctions Underlie Some Diabetic Complications
Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.
research Single-Cell RNA Profiling of Human Skin Reveals Age-Related Loss of Dermal Sheath Cells and Their Contribution to a Juvenile Phenotype
Aging reduces dermal sheath cells, affecting youthful skin appearance.
research Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis
Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.
research Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions
The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
research Biological Features Implies Potential Use of Autologous Adipose-Derived Stem/Progenitor Cells in Wound Repair and Regenerations for the Patients with Lipodystrophy
Adipose-derived stem cells can help repair tissue in lipodystrophy patients.
research The concealed side of caspases: beyond a killer of cells
Caspases do more than kill cells; they also help in cell growth and disease, and targeting them could lead to new treatments.