research In-Situ Tensile Testing of Hair Fibers in An Environmental Scanning Electron Microscope (ESEM)
Hair fibers break by cuticle cell slipping, shape changing, cuticle fraying, and surface cracking when stretched under specific conditions.
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480-510 / 1000+ results research Tissue Engineering in Cosmetics and Dermatology: A New Era of Innovation and Application
Tissue engineering in cosmetics offers safer, more effective products and ethical alternatives to animal testing.
research Comparison of two in vitro models for the analysis of follicular penetration and its prevention by barrier emulsions
Pig ear skin is better than human skin for testing how well barrier creams block allergens from entering hair follicles.
research Optimization of Gelatin and Crosslinker Concentrations in a Gelatin/Alginate-Based Bioink with Potential Applications in a Simplified Skin Model
A bioink with 15% gelatin and 150 mM calcium chloride works best for 3D printing skin models.
research Culture of the human pilosebaceous unit, hair follicle and sebaceous gland
The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–like Autoimmune Disease
AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
research Inhibition of 5α-Reductase Activity in SZ95 Sebocytes and HaCaT Keratinocytes In Vitro
The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.
research Parenteral and Oral Cyproterone Acetate Treatment in Severe Hirsutism
Cyproterone acetate implants were more effective at reducing facial hair and improving skin in severe hirsutism than oral treatment.
research Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid
Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.
research Exosomes
Exosome therapies could help with skin and hair issues, but more testing is needed.
research Current Protocols: Alopecia Areata Mouse Models for Drug Efficacy and Mechanism Studies
The C3H/HeJ mouse model is useful for studying and testing treatments for alopecia areata.
research Eflornithine Hydrochloride-Loaded Electrospun Nanofibers as a Potential Face Mask for Hirsutism Application
The new face mask with Eflornithine can potentially reduce facial hair growth and moisturize skin.
research Allergens and Irritants
Many substances, including chemicals and metals, can cause skin reactions; careful handling and identification of allergens are crucial to prevent dermatitis.
research Alopecia por diluição da cor em uma cadela Staffordshire Bull Terrier azul: Relato de caso
A blue Staffordshire Bull Terrier had hair loss due to color dilution alopecia, confirmed by tests, but no treatment was pursued.
research 890 Development of pigmented reconstructed human epidermis model containing human melanoblasts from keratinocyte culture
The created skin model with melanoblasts improves the study of skin color and offers an alternative to animal testing.
research Clinical and epidemiological characteristics and condition of the hormonal status in women with androgenetic alopecia (1139.3)
Women with androgenetic alopecia often have other symptoms of high androgen levels, requiring further hormone testing.
research RETRACTED: High‐powered 675‐nm laser: Safety and efficacy in clinical evaluation and in vitro evidence for different skin disorders
The study's findings are unreliable due to retraction.
research Preclinical Results of the Potential Role of Exolight Exosomes as Adjuvant Therapy of CO2 Laser Application for Skin Aging Management
The collagen booster may improve healing after CO2 laser treatment for skin aging.
research Targeting the Complexity of In Vitro Skin Models: A Review of Cutting-Edge Developments
In vitro skin models are improving but still need more innovation to fully replicate human skin.
research 595 In vitro evaluation of skin distribution and human dermal papilla cells proliferation for minoxidil 5% topical lotion hydrogel
The new minoxidil hydrogel is a promising alternative for hair loss treatment, with similar effectiveness and less skin irritation.
research Tanshinone, a Natural NADPH Oxidase Inhibitor, Mitigates Testosterone-Induced Hair Loss
Tanshinone compounds can help prevent hair loss caused by testosterone.
research The Antiandrogenic Action of 4–Androsten–3–one–17β– Carboxylic Acid and Its Methyl Ester on Hamster Flank Organ1
The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.
research Novel skin patch combining human fibroblast-derived matrix and ciprofloxacin for infected wound healing
The new skin patch with human matrix and antibiotic improves wound healing.
research Biorevitalizing effect of a novel facial serum containing apple stem cell extract, pro‐collagen lipopeptide, creatine, and urea on skin aging signs
The serum improved skin aging signs by enhancing cell metabolism and reducing wrinkles.
research Evaluating hair growth promoting effects of candidate substance: A review of research methods
The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.
research Congenital adrenal hyperplasia
The document concludes that diagnosing and treating Congenital Adrenal Hyperplasia is complex and requires a team approach due to its effects on the skin and other symptoms.
research Hyaluronic acid (HA)-based hydrogels for full-thickness wound repairing and skin regeneration
Hyaluronic acid-based HA2 hydrogel helps heal skin wounds better with less scarring.
research Metabolic and hormonal effects of a combined Myo-inositol and d-chiro-inositol therapy on patients with polycystic ovary syndrome (PCOS)
The combined Myo-inositol and D-chiro-inositol treatment improved weight, hormone levels, and skin conditions in women with PCOS.
research Optimized skin optical clearing for optical coherence tomography monitoring of encapsulated drug delivery through the hair follicles
A PEG-400/oleic acid mixture best improves drug delivery monitoring through hair follicles.
research Epidermis reconstructed from the outer root sheath of human hair follicle. Effect of retinoic acid
Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.