April 2018 in “Journal of Investigative Dermatology” IL-17C is important in inflammatory skin diseases and could be a target for treatment.
84 citations
,
October 2014 in “PLoS Genetics” Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.
1 citations
,
June 2018 in “International Journal of Contemporary Pediatrics” Poor nutrition in young children causes skin and hair issues, highlighting the need for better nutrition education.
64 citations
,
July 2016 in “Journal of Immunology” Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.
144 citations
,
November 2020 in “Frontiers in immunology” Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
59 citations
,
June 2022 in “Frontiers in medicine” There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
35 citations
,
August 2010 in “The American journal of pathology” Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.
31 citations
,
March 2013 in “Gene” Signaling pathways are crucial for hair growth in goats.
2 citations
,
October 2023 in “Dermatology practical & conceptual” More research is needed to understand hair and scalp disorders in people with skin of color.
2 citations
,
September 2023 in “JMIR. Journal of medical internet research/Journal of medical internet research” Machine learning can predict symptoms and quality of life in chronic skin disease patients using smartphone app data, and shows that app use varies with patient characteristics.
1 citations
,
September 2025 in “Clinical Cosmetic and Investigational Dermatology” Adipose-derived stem cell exosomes and AI can improve personalized skincare by offering anti-aging benefits and precise product customization.
1 citations
,
March 1997 in “Journal of Chromatography B: Biomedical Sciences and Applications” Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.
April 2018 in “Journal of Investigative Dermatology” Cutaneous lupus patients have higher levels of certain immune cells in their blood and skin.
April 2017 in “Journal of Investigative Dermatology” The document concludes that various topical treatments show promise for skin conditions like atopic dermatitis, psoriasis, and hair loss.
8 citations
,
November 2020 in “Nature Communications” Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
33 citations
,
February 1996 in “Journal of The American Academy of Dermatology” Treat scalp and beard fungal infections early with oral antifungal medication and sometimes topical therapy, avoiding unnecessary allergy tests and surgery.
8 citations
,
June 2019 in “Pharmaceutical research” Applying heat with certain chemicals can greatly improve how well isotretinoin gets into the skin through hair follicles.
5 citations
,
May 2019 in “Archives of Dermatological Research” Narrowband UVB treatment increases certain gene expressions in psoriasis skin and improves symptoms.
May 2019 in “Pakistan Journal of Pharmaceutical Sciences” CO2 laser treatment may be more effective for skin rejuvenation.
January 2018 in “Springer eBooks” PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
14 citations
,
April 2005 in “Experimental Dermatology” Stressed fibroblasts greatly increase melanin production in hair, skin, and eye cells, mainly due to a growth factor called bFGF.
February 2026 in “Clinical Cosmetic and Investigational Dermatology” Inverted Follicular Keratosis is rare but should be considered in scalp lesion diagnoses for all ages.
326 citations
,
February 2009 in “The American journal of pathology” Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.
92 citations
,
June 2010 in “Journal of The American Academy of Dermatology” Dutasteride 0.5 mg daily improves hair growth safely in men with hair loss.
68 citations
,
August 2014 in “Stem Cells Translational Medicine” Dermal papilla cells help wounds heal better and can potentially grow new hair.
62 citations
,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
32 citations
,
March 2014 in “PLOS ONE” Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
18 citations
,
April 2022 in “Frontiers in bioengineering and biotechnology” Gelatin microspheres with stem cells speed up healing in diabetic wounds.
14 citations
,
December 2007 in “Pediatric allergy and immunology” Newborns with the common rash Erythema Toxicum have many active mast cells in their skin, but these cells don't produce the LL-37 peptide.
January 2025 in “Scripta Medica” PDO, PLLA, and PCL threads increase collagen in ageing skin but don't change MMP1 gene expression.