research Effect of P144® (Anti-TGF-β) in an “In Vivo” Human Hypertrophic Scar Model in Nude Mice
P144® improves hypertrophic scars by reducing size and thickness and increasing elasticity.
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research A systematic summary of survival and death signalling during the life of hair follicle stem cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research Liposomal honokiol promotes hair growth via activating Wnt3a/β-catenin signaling pathway and down regulating TGF-β1 in C57BL/6N mice
Liposomal honokiol helps hair regrowth by activating certain pathways and reducing specific proteins.
research Distinct transcriptomic landscapes of cutaneous basal cell carcinomas and squamous cell carcinomas
Basal cell carcinomas and squamous cell carcinomas have different gene activity patterns, suggesting unique treatment approaches.
research The Aldo-Keto Reductase AKR1B10 Is Up-Regulated in Keloid Epidermis, Implicating Retinoic Acid Pathway Dysregulation in the Pathogenesis of Keloid Disease
AKR1B10 enzyme may cause keloid scars and could be a treatment target.
research MSCs and their exosomes: a rapidly evolving approach in the context of cutaneous wounds therapy
MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.
research Stem Cell Therapy for Burns: Story so Far
Stem cell therapy shows promise in improving burn wound healing.
research Differentiation of human hair follicle stem cells into endothelial cells induced by vascular endothelial and basic fibroblast growth factors
Human hair follicle stem cells can become endothelial cells with certain growth factors, useful for vascular treatments.
research THY1-mediated mechanisms converge to drive YAP activation in skin homeostasis and repair
Targeting THY1 can improve skin repair and healing.
research Feasibility of repairing full-thickness skin defects by iPSC-derived epithelial stem cells seeded on a human acellular amniotic membrane
iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
research Activin B Stimulates Mouse Vibrissae Growth and Regulates Cell Proliferation and Cell Cycle Progression of Hair Matrix Cells through ERK Signaling
Activin B can boost hair growth by promoting cell proliferation and cell cycle progression.
research 3D bioprinting of engineered exosomes secreted from M2-polarized macrophages through immunomodulatory biomaterial promotes in vivo wound healing and angiogenesis
3D bioprinting with special hydrogels helps heal wounds and grow new blood vessels.
research Loss of Msx2 Function Down-Regulates the FoxE3 Expression and Results in Anterior Segment Dysgenesis Resembling Peters Anomaly
Loss of Msx2 function causes eye development issues similar to Peters anomaly.
research Epidermal stem cells: skin surveillance and clinical perspective
Epidermal stem cells are vital for skin healing and have potential for treating skin disorders.
research Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-β1 and platelet-derived growth factor BB
Human hair follicle stem cells can become smooth muscle cells using specific growth factors.
research Antler stem cell-derived exosomes promote regenerative wound healing via fibroblast-to-myofibroblast transition inhibition
Antler stem cell exosomes improve wound healing and reduce scarring.
research Effectiveness of Extracellular Vesicle Application in Skin Aging Treatment and Regeneration: Do We Have Enough Evidence from Clinical Trials?
Extracellular vesicles show promise in skin treatments but need more research and standardization.
research Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea
Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
research A review on the chemical constituents and pharmacological efficacies of Lindera aggregata (Sims) Kosterm
Lindera aggregata has many beneficial compounds that can help prevent and manage diseases.
research Lentiviral Arrays for Live-cell Dynamic Monitoring of Gene and Pathway Activity During Stem Cell Differentiation
The lentiviral array can monitor and predict gene activity during stem cell differentiation.
research Perspectives on miRNAs Targeting DKK1 for Developing Hair Regeneration Therapy
Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.
research Identification and characterization of four immune-related signatures in keloid
Four specific genes are linked to keloid formation and could be potential treatment targets.
research A hybrid hydrogel encapsulating human umbilical cord mesenchymal stem cells enhances diabetic wound healing
A new hydrogel with stem cells from the human umbilical cord speeds up healing in diabetic wounds.
research Association of single nucleotide polymorphisms in the RAB5B gene 3′UTR region with polycystic ovary syndrome in Chinese Han women
Certain genetic variations in the RAB5B gene are linked to a higher risk of polycystic ovary syndrome in Chinese Han women.
research A pair of transmembrane receptors essential for the retention and pigmentation of hair
Bmpr2 and Acvr2a receptors are crucial for hair retention and color.
research Overview of Nanocosmetics with Emphasis on those Incorporating Natural Extracts
Nanocosmetics with natural extracts offer benefits but need more research on safety and environmental impact.
research Exosome-based cell therapy for diabetic foot ulcers: Present and prospect
Exosomes show promise for healing diabetic foot ulcers.
research Sox2 in the dermal papilla regulates hair follicle pigmentation
Sox2 controls hair color by affecting pigment production in hair follicles.
research Carbon dots with tissue engineering and regenerative medicine applications
Carbon dots show promise for tissue repair and growth but need more research to solve current challenges.
research Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature
New regenerative treatments for hair loss show promise but need more research for confirmation.