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GlossarySodium Dodecyl Sulfate

synthetic detergent and surfactant used in shampoos and cleaning products

Sodium Dodecyl Sulfate (SDS), also known as Sodium Lauryl Sulfate (SLS), is a synthetic detergent and surfactant commonly used in cleaning products, shampoos, and toothpaste. It works by lowering the surface tension of water, allowing it to more effectively remove oils and dirt. In scientific research, SDS is also used in protein denaturation during SDS-PAGE, a technique for separating proteins based on their molecular weight.

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Electrophoretic Variability in Human Head Hair: Polyacrylamide Gel Electrophoresis of Hair Proteins in the Presence of Sodium Dodecyl Sulfate and Urea

research Electrophoretic variability in human head hair: Polyacrylamide gel electrophoresis of hair proteins in the presence of sodium dodecyl sulfate and urea

15 citations , January 1987 in “Electrophoresis”

Human head hair proteins can be typed into eight distinct patterns, useful for genetic and forensic investigations.

Electrophoretic Variability in Human Hair: Comparative Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis of Body and Head Hair Proteins

research Electrophoretic variability in human hair: Comparative sodium dodecyl sulfate‐polyacrylamide gel electrophoresis of body and head hair proteins

11 citations , January 1987 in “Electrophoresis”

Keratin proteins are consistent across different hair types from the same person.

In Vitro and In Vivo Evaluation of Biologically Synthesized Silver Nanoparticles for Topical Applications: Effect of Surface Coating and Loading into Hydrogels

research In vitro and in vivo evaluation of biologically synthesized silver nanoparticles for topical applications: effect of surface coating and loading into hydrogels

130 citations , January 2017 in “International journal of nanomedicine”

Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.

research Cross-linked features of mouse pelage hair resistant to detergent extraction

15 citations , February 1999 in “The anatomical record”

Some mutant mice have hair with abnormal cross-linking, mainly in the cuticle, not affecting other hair parts.

research Demethylation of methionine and keratin damage in human hair

11 citations , February 2018 in “Amino acids”

Copper and iron cause keratin damage in hair by converting methionine to homocysteine.

research Hair removal and bioavailability of chemicals: Effect of physicochemical properties of drugs and surfactants on skin permeation ex vivo

10 citations , June 2019 in “International Journal of Pharmaceutics”

Hair removal methods damage the skin barrier and affect substance penetration.

research Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice

5 citations , September 2018 in “International journal of genomics”

Genetic mutations that disrupt homocysteine breakdown lead to increased damage in mouse hair keratin.

research The microfibrillar proteins of human hair: Separation by high-performance liquid chromatography and isolation of some proteins enriched in glycine and tyrosine

2 citations , August 1987 in “Analytical Biochemistry”

A new method isolated previously undetected hair proteins rich in glycine and tyrosine.

research Core–Sheath Nanofibers From a Modified Coaxial Electrospinning for Transdermal Delivery of Finasteride

June 2026 in “ChemistryOpen”

Modified nanofibers improve finasteride skin absorption.

research Protolytic Equilibria of Cetirizine in the Presence of Micelle-Forming Surfactants

January 2025 in “Organics”

Micelles can change cetirizine's ionization, affecting its effectiveness in treatments.

research Characterization of hair lipid and protein dynamics using EPR spectroscopy and treatment effects

December 2023 in “Journal of molecular structure”

Hair treatments and dehydration affect hair's lipid and protein behavior, influencing its flexibility and appearance.

research Synchronous fluorescence as a green and selective method for the simultaneous determination of finasteride and tadalafil in dosage form and spiked human plasma

May 2023 in “Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy”

A new green method accurately measures finasteride and tadalafil in drugs and plasma.

research Improved forensic hair evidence for drugs of abuse by mass spectrometry

January 2016

Forensic hair analysis for drugs is now more reliable and accurate.

research Cross‐linked features of mouse pelage hair resistant to detergent extraction

February 1999 in “The anatomical record”

Two mouse mutants have defective hair cuticle cross-linking.

research Inheritance of Some Electrophoretic Phenotypes of Human Hair

January 1990 in “Advances in forensic haemogenetics”

Human hair protein patterns are inherited genetically.

research Determination of Free Chemical Potential for Finasteride Diffusion through SDS Micelle Suggested as Alternative Living Membrane System

August 2022 in “International journal of membrane science and technology”

Finasteride diffuses spontaneously through SDS micelles, suggesting they can replace living cell membranes.

research Fluorescence Microscopy Study of the Sorption of Cationic Polymers on Hair

1 citations , August 1999 in “ACS symposium series”

Polymer JR400 sticks to hair but washes off with detergent.

research Polyphenol–Inorganic Sulfate Complex-Enriched Straightening Shampoo for Reinforcing and Restoring Reduced Hair Integrity

February 2025 in “Biomimetics”

The shampoo straightens hair while keeping it healthy and less damaged.

research Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil

53 citations , January 1993 in “Biochemical Pharmacology”

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

Gelatin-Chondroitin-6-Sulfate-Hyaluronic Acid Scaffold Seeded with Vascular Endothelial Growth Factor 165 Modified Hair Follicle Stem Cells as a Three-Dimensional Skin Substitute

research Gelatin-chondroitin-6-sulfate-hyaluronic acid scaffold seeded with vascular endothelial growth factor 165 modified hair follicle stem cells as a three-dimensional skin substitute

45 citations , October 2014 in “Stem cell research & therapy”

Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.

research The Novel Excipient, Dodecyl-2-N, N-dimethylaminopropionate Hydrochloride (DDAIP-HCl) Improves the Flux of Minoxidil in Human Skin

2 citations , January 2012 in “Hair therapy & transplantation”

DDAIP-HCl significantly increases minoxidil absorption into the skin.

research Biomechanics of chemically treated hair for continuous 1D strands

February 2026

NaOH treatment improves hair strength and suitability for textiles.

Comparison of Three Different Lactic Acid Bacteria-Fermented Proteins on RAW 264.7 Osteoclast and MC3T3-E1 Osteoblast Differentiation

research Comparison of three different lactic acid bacteria-fermented proteins on RAW 264.7 osteoclast and MC3T3-E1 osteoblast differentiation

December 2023 in “Scientific reports”

Fermented soy protein may help prevent bone loss by affecting bone cell activity.

Mild Cutaneous Manifestation in Two Young Women with Extraordinary Hyperandrogenemia

research Transport of Biotin in Human Keratinocytes

53 citations , March 2003 in “Journal of Investigative Dermatology”

Human skin cells have a high-affinity system for biotin transport, crucial for skin health.

research A novel purification procedure for keratin-associated proteins and keratin from human hair

54 citations , January 2013 in “Journal of Biological Macromolecules”

A new method effectively separates keratin-associated proteins and keratin from human hair.

Stability-Indicating Micellar Electrokinetic Chromatography Method for Determination of Finasteride in Pharmaceutical Preparations

research STABILITY-INDICATING MICELLAR ELEKTROKINETIC CHROMATOGRAPHY METHOD FOR DETERMINATION OF FINASTERIDE IN PHARMACEUTICAL PREPARATIONS

5 citations , February 2013 in “Journal of Liquid Chromatography & Related Technologies”

Method accurately measures finasteride concentration in medicine.

research Quantitative Analysis of Cashmere and Other Animal Hair Fibers in Textiles Using MALDI-TOF Mass Spectrometry

1 citations , January 2014 in “Sen'i Gakkaishi”

The new method reliably identifies and measures different animal hair fibers in textiles.