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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

CRISPR-Cas9 can successfully edit genes in large mammals like Cashmere goats.

Early treatment of superficial fungal infections in immunocompromised patients is crucial.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Inactivating β-catenin is essential for chick retina regeneration.

Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.

White wax and policosanol from white wax effectively reduced hair loss and promoted hair growth in mice better than a known hair growth drug.

Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

Targeting EGFR may help reduce hair loss from chemotherapy.

Both human and animal-derived small extracellular vesicles speed up skin healing equally well.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

FDG PET/CT scans can change cancer treatment plans for dogs.

The postnatal thymus has cells like mesenchymal stem cells that can become different cell types and help maintain thymus structure.

Using buccal mucosa for hypospadias repair in children is effective and reduces complications.

Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.

A cancer drug called nilotinib might cause hair loss due to inflammation around hair follicles.

The SA-MS hydrogel is a promising material for improving wound healing and skin regeneration in diseases like diabetes and skin cancer.

Corkscrew and cigarette-ash-shaped hairs in tinea capitis are caused by internal hair degradation and external resistance.

The document concludes that hair follicular unit transplantation is an effective method for eyebrow and eyelash reconstruction, with patients happy despite needing regular trimming.

Minoxidil works well as a high permeability reference drug for biopharmaceutics classification.

Vitamin D receptor helps control hair growth genes in skin cells.

Shampoos have evolved into multifunctional products with patented innovations for different hair needs and can include medicinal herbs for hair and scalp health.

Androgens can cause hair growth in some areas but hair loss on the scalp.

Dutasteride works better than finasteride for preventing and treating prostate cancer.

Dyeing hair can help target and destroy hair follicles selectively.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.