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Overexpressing SSAT in mice makes them highly sensitive to polyamine analogues, causing liver damage and high mortality.

The research identified new skin traits in mice, some linked to human skin conditions.

A specific gene mutation in KRT86 is linked to hair disorder in a Chinese Han family.

N1-acetylspermidine promotes hair follicle stem cell self-renewal.

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Protein kinase C epsilon may promote skin cancer development after UV exposure by affecting nearby cells.

Dark skin has stronger barriers and structure due to specific gene activity.

Targeting SOX proteins may improve cancer treatment by restoring immune function.

Protein kinase C epsilon may increase skin cancer risk by affecting nearby cells.

Blocking CXCR4 may help treat hidradenitis suppurativa.

Certain SPINK5 gene mutations are common in Israeli families with Comèl-Netherton syndrome.

Certain genes control the color of human hair by affecting pigment production.

The Bsk mutation doesn't involve keratin gene recombination and its cause is unknown.

A rare gene mutation causes skin fragility and itching without affecting hair or nails.

A new mutation in the PLEC gene causes a rare condition with skin blistering, muscle weakness, and hair loss.

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

Albumin and prednisone improved symptoms in a woman with Cronkhite-Canada syndrome, revealing potential genetic causes.

Genetic defects in the Wnt/PCP pathway may cause congenital yellow nail syndrome.

Scientists identified a unique type of human skin stem cell that could help with tissue repair.

Pallister-Killian Syndrome is a complex genetic disorder requiring coordinated care and genetic counseling.

Human melanocytes in skin and hair follicles don't express keratin 16 or 6 naturally.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

ETS2 is crucial in squamous cell carcinoma development and could be a therapeutic target.

Lower PPARγ levels and specific gene variations are linked to more severe Frontal Fibrosing Alopecia.

Substance P helps hair growth by extending the growth phase and affecting certain growth factors.

Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.

Certain gene variations increase the risk of alopecia areata in Koreans.

A rare genetic variant linked to skin cysts was found in blood DNA, suggesting its role in cyst formation.

Increased PHGDH expression causes early melanin buildup in hair follicles.