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research Single‐cell transcriptomic analysis of small and large wounds reveals the distinct spatial organization of regenerative fibroblasts
Different types of skin cells are organized in a special way in large wounds to help with healing and hair growth.
research Hormonal Organization of Sex Differences in Play Fighting and Spatial Behavior
Gonadal hormones may influence sex differences in play fighting in animals, but their effect on human spatial behavior is unclear and needs more research.
research 464 Spatial transcriptomics links gene expression profiles to functional and structural traits of darkly pigmented skin
Dark skin has stronger barriers and structure due to specific gene activity.
research Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation
Key skin cell regulators and gene organization changes are crucial for skin cell development and could help treat skin disorders.
research Exploring machine learning strategies for single-cell transcriptomic analysis in wound healing
Machine learning and single-cell analysis improve understanding and treatment of wound healing.
research Self‐organizing hair peg‐like structures from dissociated skin progenitor cells: New insights for human hair follicle organoid engineering and Turing patterning in an asymmetric morphogenetic field
Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.
research Efficient Generation of Skin Organoids from Pluripotent Cells via Defined Extracellular Matrix Cues and Morphogen Gradients in a Spindle‐Shaped Microfluidic Device
Scientists developed a new way to create skin-like structures from stem cells using a special 3D gel and a device that improves cell organization and increases hair growth.
research 707 Guiding skin organoid generation via extracellular matrix cues and spatially controlled morphogen gradients
Scientists improved how to make skin-like structures from stem cells using special gels and a device that controls growth signals, leading to better hair and skin features.
research A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Type II Epithelial Keratin 6hf (K6hf) Is Expressed in the Companion Layer, Matrix, and Medulla in Anagen-Stage Hair Follicles
K6hf is found in specific parts of hair follicles, nails, and tongue, and is linked to hair growth and structure.
research Sostdc1 defines the size and number of skin appendage placodes
Sostdc1 controls the size and number of hair and mammary gland structures.
research Chirality Effect on Physical and Biological Properties of Peptide-Based Hydrogels
Chirality influences the structure, strength, and biological uses of peptide-based hydrogels.
research Multi-scale modeling for cell fate specification during regeneration and development
Signaling factors and gene-driven cell adhesion are crucial for wound healing and embryo development.
research All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research Spatial Gene Profiling in the Ischemic Heart
A new technology showed that the SOX9 gene might control heart scar formation after injury, suggesting new treatment possibilities.
research Compartmentalized organization: a common and required feature of stem cell niches?
Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
research Ontogenetic Transition in Fetal Wound Transforming Growth Factor-β Regulation Correlates with Collagen Organization
Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.
research Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells
Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
research Amendments to Organizational Theorizing
Karl E. Weick recommended focusing on everyday events and smaller organizations to improve organizational theory.
research Multi-scale spatial mapping of cell populations across anatomical sites in healthy human skin and basal cell carcinoma
The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
research Amendments to Organizational Theorizing.
Karl E. Weick suggested focusing on everyday events and smaller groups to improve organizational theory and urged the inclusion of nonobvious aspects for better explanations.
research Deciphering principles of morphogenesis from temporal and spatial patterns on the integument
The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
research Molecular and spatial design of early skin development
The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
research Spatial transcriptomics of a giant pilomatricoma
The analysis of a large pilomatricoma revealed five distinct areas with different gene activity related to hair growth and tumor development.
research The Epithelial Stem Cell Niche in Skin
Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
research From a stem-cell–centered to a niche-centered view: the core role of collagen networks in hair loss and hair follicle miniaturization
Collagen networks play a key role in hair loss and follicle miniaturization.
research Disturbance of Immune Microenvironment in Androgenetic Alopecia through Spatial Transcriptomics
Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.
research Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations
Researchers found four distinct fibroblast types in human skin, which could help in treating wounds and fibrotic diseases.
research Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes
The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.