research Utility of caffeine analysis for forensic hair discrimination
Caffeine in hair might help identify people, but it's not always reliable.
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research Estimation methods for human circadian phase by use of peripheral tissues
New method uses hair follicle cells to estimate human body clock phase, potentially improving sleep disorder diagnosis.
research ToF‐SIMS characterization of the lipid layer on the hair surface. I: the damage caused by chemical treatments and UV radiation
Chemical treatments and UV radiation severely damage the lipid layer on hair.
research Aplikasi Konsep Difraksi dalam Bidang Kesehatan
Light diffraction helps in eye surgery, brain treatments, and detecting hair loss and genetic diseases.
research How storage post sampling influences the stability of sebum when used for mass spectrometry metabolomics analysis?
Sebum samples remain stable under various storage conditions, making them suitable for remote and at-home testing.
research P08 Developing a rapid ATP assay to understand skin and hair follicle microbiome and assess skin microbiome dysbiosis
This study developed a rapid ATP assay to assess skin microbiome dysbiosis, involving 5 healthy volunteers. Dysbiosis was induced using tape stripping and ethanol wiping, with samples collected at various intervals. The ATP assay effectively measured microbial populations, showing that both methods induced dysbiosis, which recovered over 24 hours. However, ethanol-treated skin took longer to recover than tape-stripped skin. The assay could potentially be used as a clinical tool to assess microbiome recovery rates, though further research is needed to explore its application in diseased skin and the feasibility of a handheld ATP device for clinical use.
research Polarized Versus Diffractive Microscopy in Distinguishing Scarring From Non‐Scarring Alopecia
This study evaluated the effectiveness of polarized light microscopy versus diffractive microscopy in diagnosing alopecia using 152 scalp biopsy slides. Polarized light microscopy demonstrated superior performance in distinguishing between scarring and non-scarring alopecia, with a high specificity of 94.9% and an AUC of 0.804, compared to diffractive microscopy, which had an AUC of 0.585. The intensity of polarization provided clearer separation between the two types of alopecia, making it a valuable tool in histologic diagnosis. Additionally, a circumferential perifollicular halo was more frequently observed in non-scarring alopecia, particularly in androgenetic alopecia.
research Preparation of Finasteride via Oxidative Elimination of 2-Iododihydrofinasteride by Using Peroxydisulfates as Oxidizing Agents
Using K2S2O8 as an oxidizing agent in a specific condition, we can make Finasteride with 96.3% yield and 99.6% purity. This method is also good for other compounds and is environmentally friendly.
research LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery
A new, quick method was developed to analyze skin lipids, discovering a new ceramide subclass.
research Raman spectroscopy reveals biophysical markers in skin cancer surgical margins
Raman spectroscopy can help identify cancerous skin tissue during surgery.
research Elevated carbon dioxide levels lead to proteome-wide alterations for optimal growth of a fast-growing cyanobacterium, Synechococcus elongatus PCC 11801
Higher CO2 levels help a cyanobacterium grow better by boosting photosynthesis and carbon uptake.
research Análise de esteróides em extratos vegetais e estudo fitoquímico e biológico preliminar de Brunfelsia uniflora.
Brunfelsia uniflora has good antioxidant properties and moderate antibacterial activity.
research Safety of a Perfluorodecalin-Infused Silicone Patch in Picosecond Laser-Assisted Tattoo Removal
research Hair removal evaluated with a filterless flashlamp‐based system: a preliminary study in 10 patients
The filterless flashlamp-based system effectively delays hair regrowth and improves skin condition.
research A novel method for visualizing hair lipids at the cell membrane complex: Argon sputter etching/scanning electron microscopy1
The method shows how hair lipids form specific patterns and their roles in hair structure.
research CSI on steroids
Forensic DNA phenotyping can help generate new leads in cold cases but faces accuracy, legal, and acceptance challenges.
research Examining the Utility of LA-ICP-MS for Detection of Time-resolved Zinc Exposures and Determination of Hair Growth Rate
LA-ICP-MS effectively measures zinc, lead, and mercury in hair.
research Tacrolimus monitoring in hair samples of kidney transplant recipients
Hair samples can reliably monitor tacrolimus levels in kidney transplant patients.
research A New Assessment Method of Vitiligo by Combination of Dermoscopy and Reflectance Confocal Microscopy
The new method combining dermoscopy and Reflectance Confocal Microscopy is more effective for evaluating vitiligo.
research Visual imaging of calcium ion distribution in acetone and tape stripping damaged canine epidermis.
The method visualized calcium ions in damaged canine skin, showing potential for studying skin recovery.
research Cost-effectiveness analysis of laboratory monitoring in newly diagnosed telogen effluvium patients
Targeted testing for telogen effluvium patients can save healthcare costs.
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research Analysis of hair follicle penetration of lidocaine and fluorescein isothiocyanate-dextran 4 kDa using hair follicle-plugging method
Hair follicles are important for the absorption of certain drugs into the skin.
research Mechanistic study of decreased skin penetration using a combination of sonophoresis with sodium fluorescein-loaded PEGylated liposomes with D-limonene
Using sonophoresis can make it harder for certain drug-loaded liposomes to get through the skin.
research Comprehensive Spectroscopic Characterization of Finasteride Polymorphic Forms. Does the Form X Exist?
Three finasteride forms exist; "form X" doesn't.
research Determination of Finasteride in Human Plasma by HPLC-MS and Study on the Bioequivalence of Domestic and Import Finasteride Tablets
Domestic and imported finasteride tablets are bioequivalent.
research Attenuated Total Reflection Fourier Transform Infrared Spectroscopy Analysis of Human Hair Fiber Structure
Human hair has different protein structures in its cuticle and cortex.
research Three-Dimensional Dynamic MR-Hysterosalpingography: A New, Low Invasive, Radiation-Free and Less Painful Radiological Approach to Female Infertility
This new method makes checking for female infertility less painful, less invasive, and doesn't use radiation.
research Forensic chemical study on human hair. IV. Identification of brand of hair sprays and hair growth promoters by components remaining on human hair, and example of forensic hair examination.
Chemical analysis of hair products on human hair can help identify specific brands and link suspects to victims.
research Measuring steroids in hair opens up possibilities to identify congenital adrenal hyperplasia in developing countries
Hair steroid measurement is an effective method to diagnose and monitor CAH in developing countries.