research Immunofluorescence analysis of the basement membrane zone components in human anagen hair follicles
The upper hair follicle is stable, while the lower part allows movement during hair growth.
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450-480 / 1000+ resultsresearch 0887 Long-lived and genetically-diverse skin organoids derived from murine adult hair follicle stem cells
Researchers created long-lasting, diverse skin organoids from mouse hair follicle stem cells, useful for studying skin.
research Evolutionary Trees of Intermediate Filament Proteins
research Regeneration of a bioengineered 3D integumentary organ system from iPS cells
Scientists created a functional 3D skin system from stem cells that can be transplanted into wounds.
research MicroRNA profiles of four induced pluripotent stem cell lines derived from distinct tissues
iPSC lines from different tissues share a common miRNA profile, supporting their pluripotent nature.
research Aligned membranes regulate wound healing via MMP12 secreted by macrophages
Aligned membranes improve wound healing by reducing scars and promoting skin regeneration.
research Fully functional hair follicle organ regeneration using organ-inductive potential stem cells with an accessory mesenchymal cell population in an in vitro culture system
Scientists successfully regenerated functional hair follicles using specific stem cells and mesenchymal cells.
research 560 Isolation of an “early” transit amplifying keratinocyte population in interfollicular human epidermis: a role for CD271 receptor
Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.
research Self-assembled monolayer enhanced support-free two-photon polymerisation for microscale kinematic pairs
A new method creates precise, stable microscale structures with reduced friction and potential for complex designs.
research Trps1 activates a network of secreted Wnt inhibitors and transcription factors crucial to vibrissa follicle morphogenesis
Trps1 is essential for proper hair follicle development.
research Dynamic expression patterns of tenascin, proteoglycans, and cell adhesion molecules during human hair follicle morphogenesis
Specific proteins and molecules play key roles in the development of human hair follicles.
research Direct cellular reprogramming enables development of viral T antigen–driven Merkel cell carcinoma in mice
Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.
research A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease
Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
research 1376 A multi-scale spatial atlas of human skin links cancer cell states to site of origin
The research shows that skin cancer likely originates from hair follicles and that certain cell populations expand to promote skin cancer growth.
research Non-canonical Wnt signaling promotes directed migration of intestinal stem cells to sites of injury.
Special gut cells help stem cells move to and fix injured areas by activating a specific signaling pathway.
research 545 Skin Organoids derived from NCSTN mutated patient-induced pluripotent stem cells recapitulate Hidradenitis Suppurativa pathogenic hallmarks
Skin organoids with NCSTN mutation show changes in hair follicle development and higher inflammation, key features of Hidradenitis Suppurativa.
research Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle
Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
research Follicular dermal papilla structures by organization of epithelial and mesenchymal cells in interfacial polyelectrolyte complex fibers
Scientists created 3D hair-like structures that could help study hair growth and test treatments.
research A Novel Device to Insert FU Grafts into Premade Sites
Dr. Parsa Mohebi created a new tool to improve hair transplant efficiency and reduce follicle damage.
research 864 Catalytic-dependent and -independent activities of Polycomb repressive complex 1 differentially regulate skin stem cell specification
PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.
research Molecular heterogeneity of quiescent melanocyte stem cells revealed by single-cell RNA-sequencing
Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.
research Multilayered Gel-Spotting Device for In Vitro Reconstruction of Hair Follicle-like Microstructure
The new method can create hair follicle-like structures but not complete hair with roots and shafts, needing more improvement.
research H3K9me3 controls epidermis morphogenesis by regulating RNA Pol II dynamics at developmental promoters and enhancers
H3K9me3 is crucial for proper skin development and structure.
research Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity
Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.
research PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis
PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
research Injury and stress responses of adult neural crest-derived cells
Adult neural crest-derived cells can become multipotent and aid tissue repair when stressed or injured.
research Melanocyte Chitosan/Gelatin Composite Fabrication with Human Outer Root Sheath-Derived Cells to Produce Pigment
The technique can isolate cells to help treat skin pigmentation issues.
research A Concise Review of Organoid Tissue Engineering: Regenerative Applications and Precision Medicine
Organoids can revolutionize medicine by modeling diseases and aiding in personalized treatments.
research Author response: Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria
FoxA is crucial for pharynx regeneration in planarian flatworms.
research Morphological study in a mechanism of congenital pili torti formation: Björnstad syndrome
Björnstad syndrome causes twisted hair from birth.