research A methodological exploration of distinguishing hair quality based on hair proteomics
Bleaching damages hair by reducing the quality of keratin and keratin-associated proteins.
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870-900 / 1000+ results research Author response: Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ
Loss of Dnmt3a and Dnmt3b leads to more aggressive skin tumors, but blocking PPAR-γ can reduce this effect.
research High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders
CEP135 may predict cancer outcomes, and targeting PLK1 could help treat certain sarcomas.
research A new hair follicle-derived human epidermal model for the evaluation of sunscreen genoprotection
The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.
research Inhibition of Polyamine Synthesis Alters Hair Follicle Function and Fiber Composition
Polyamines, especially spermidine, are essential for hair growth.
research Condylomata acuminata of HIV-positive men may harbour focal areas of dysplasia: relevant implications for the management of human papillomavirus-induced disease in high-risk patients
Warts in HIV-positive men can have serious abnormal cell growth, needing careful analysis and treatment to prevent cancer.
research 766 H3K9me3 methyltransferase SETDB1 controls retrotransposon silencing, DNA methylation, constitutive heterochromatin maintenance and 3D-chromatin structure in epidermal keratinocytes
SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.
research Baldness and testicular cancer: the EPSAM case-control study
Bald men may have a lower risk of testicular cancer.
research Contaminants of emerging concern in the fetal environment
Fetal environments contain various chemicals that may disrupt hormones.
research 1397 LSD1 is critical for epidermal development and skin barrier formation
LSD1 is essential for healthy skin development and creating the skin's protective barrier.
research Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.
A point mutation in the androgen receptor gene causes complete androgen insensitivity.
research Impacto de dutasteride en la espematogénesis y el estrés oxidativo en ratas.
Dutasteride does not seem to change rat spermatogenesis or oxidative stress.
research Isolation and Characterization of a Fetal-Maternal Microchimeric Stem Cell Population in Maternal Hair Follicles Long after Parturition
Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.
research The laboratory in the multidisciplinary diagnosis of differences or disorders of sex development (DSD)
Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.
research Peer Review #1 of "Potential use of human hair shaft keratin peptide signatures to distinguish gender and ethnicity (v0.1)"
Keratin peptides in hair may help identify gender and ethnicity, but more research is needed.
research 602 Sox13 is a novel marker for hair follicle development and differentiation
Sox13 is a new marker for early hair follicle development and differentiation.
research A preview of selected articles
The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.
research PD29-07 DRUGS ASSOCIATED THE MOST WITH MALE-FACTOR INFERTILITY: ASSESSMENT OF THE 2010-2020 FOOD AND DRUG ADMINISTRATION (FDA) PHARMACOVIGILANCE DATABASE
Finasteride and testosterone are the drugs most linked to male infertility, but many other potential drugs may be under-reported.
research Valproic acid teratogenicity in whole embryo culture is not prevented by zinc supplementation
research In vivo alteration of the keratin 17 gene in hair follicles by oligonucleotide‐directed gene targeting
Altering the keratin 17 gene in mice hair follicles caused temporary hair issues, but changes were minimal and short-lived.
research Multiomics global landscape of stemness-related gene clusters in adipose-derived mesenchymal stem cells
Young donor, early passage stem cells have the highest stemness.
research PRC 2 preserves intestinal progenitors and restricts secretory lineage commitment
PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.
research DSC-investigations of alpha-keratins and the specific effects of chemical treatments on human hair
Chemical treatments weaken hair's thermal stability and structure.
research Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway
Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.
research Effect of Disulfide Bonds in Human Hair Fibers on the Melting Behavior of Their Crystalline Structure
Changing disulfide bonds in human hair affects its melting behavior and thermal stability.
research N1-acetylspermidine is a determinant of hair follicle stem cell fate
N1-acetylspermidine promotes hair follicle stem cell self-renewal.
research Role of 5α-dihydrotestosterone in testicular development of gilthead seabream following finasteride administration
DHT affects testicular development and regulates spermatogenesis in some fish.
research El finasteride como control positivo en estudios de reproducción
Finasteride causes reproductive changes in male rats.
research Effect of disulfide bonds in human hair fibers on the melting behavior of their crystalline structure
Disulfide bonds affect the melting behavior of hair's crystalline structure, but hair retains some stability even after these bonds are broken.
research 102 Methylation of CpG islands in promoter of type 2 5-α reductase and implications of finasteride resistance for BPH therapy
Methylation in specific gene region causes finasteride resistance in some BPH patients.