34 citations
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January 2004 in “Revista do Hospital das Clínicas” Finasteride may worsen infertility in men with existing issues, but stopping it can improve sperm health.
37 citations
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January 1991 in “Reproductive Toxicology” Finasteride reduces male rat fertility by causing issues with copulatory plug formation.
Finasteride impairs sperm quality and fertility in rats, even after stopping treatment.
1 citations
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October 2024 in “BMJ Case Reports” Fertility-preserving surgery can help women with early-stage Sertoli-Leydig cell tumors conceive naturally.
January 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” More research is needed to make sperm DNA fragmentation a reliable tool for diagnosing male infertility.
October 1988 in “Pediatric research” Certain maturity signs appear before and after the first release of sperm in boys.
February 2026 in “Andrology” Post-orchidectomy semen has better DNA integrity for fertility treatments.
2 citations
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January 2015 in “Springer eBooks” Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.
5 citations
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September 2024 in “Stem Cell Research & Therapy” Sertoli cell transplants can reduce inflammation and improve sperm quality.
67 citations
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April 1988 in “The Journal of Clinical Endocrinology & Metabolism” A subtle androgen receptor abnormality can allow normal male development and sometimes fertility despite partial androgen resistance.
January 2016 in “ISBN: 978-84-608-9184-0” 2 citations
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October 1999 in “The Journal of Urology” Long-term finasteride use may affect sperm structure and chromosomes.
2 citations
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August 2021 in “The Journal of Urology” The procedure involving seminal vesiculoscopy, TURED, and balloon dilation effectively treated a man's hematospermia and improved his dysorgasmia.
April 2022 in “The Journal of Sexual Medicine” Treating hematospermia can improve sexual function and reduce anxiety.
70 citations
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April 2014 in “Annales d'endocrinologie” New genes and pathways are important for testosterone production and male sexual development.
1 citations
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January 2002 in “Yaoxue jinzhan” Finasteride reduces sperm count and affects male reproductive function, while Epristeride does not.
January 2026 in “Frontiers in Pharmacology” Certain drugs can cause male infertility, so fertility counseling and sperm preservation are advised.
54 citations
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May 2001 in “Journal of Investigative Dermatology” Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.
2 citations
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September 2017 in “Archives of Medical Science” Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.
6 citations
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June 2014 in “PubMed” Combining TUSV with finasteride effectively treats recurrent hemospermia.
December 2023 in “Urogenital tract infection” Seminal bacteria can lower sperm quality in subfertile men.
2 citations
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April 2019 in “Journal of Internal Medicine” Men using steroids or finasteride to look more attractive may harm their fertility and sexual function, creating a paradox where they seem fit but may be less able to reproduce.
February 2026 in “European Urology”
10 citations
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September 2008 in “Andrologia” Finasteride changes antioxidant enzyme expression, possibly affecting sperm protection in rats.
April 2019 in “Journal of the Endocrine Society” Mosaic Klinefelter syndrome can affect male fertility and may be missed in routine tests.
March 2013 in “Reactions Weekly” A man's fertility improved after he stopped taking finasteride but worsened again when he restarted the medication.
1 citations
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May 2024 in “The Journal of Sexual Medicine” Clomiphene Citrate can quickly restore fertility in some men after long-term steroid abuse.
August 2015 in “Dermatologica Sinica” Men with severe hair loss may have poorer sperm quality.
48 citations
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February 2006 in “Molecular and Cellular Endocrinology” 5α-reductase inhibitors may reduce male fertility and could be used for male contraception.