Finasteride significantly reduced sperm production and caused testicular atrophy in hamsters.
June 1998 in “Biomedicine & Pharmacotherapy” Medical treatments like chemotherapy and radiotherapy can harm sperm production, so freezing sperm before treatment is important for men who want children later.
September 2024 in “Reproduction and Fertility” New methods may speed up drug development for male subfertility.
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January 2004 in “PubMed” DHT deficiency in rats reduces sperm content and affects testis structure over time.
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January 2025 in “The World Journal of Men s Health” Intratesticular PRP injections are safe but not proven to improve sperm retrieval in certain infertile men.
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January 2010 in “Clinica Veterinaria De Pequenos Animales” The dog's fertility was restored with antibiotics and finasteride treatment.
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March 2001 in “PubMed” Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.
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January 2004 in “Korean Journal of Andrology” 48 citations
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December 2019 in “Reproductive Biology and Endocrinology” More research is needed to confirm sperm DNA fragmentation as a reliable tool for diagnosing male infertility.
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March 2021 in “Reproduction” Finasteride may affect male fertility by interfering with specific sperm signaling.
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September 1996 in “PubMed” 
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April 2011 in “Folia Histochemica et Cytobiologica” DHT deficiency can disrupt cell connections in rat testes, possibly affecting fertility.
January 2001 in “亚洲男性学杂志：英文版” Men's fertility and sexual health decline with age, but some remain fertile into their eighties.
June 2011 in “Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)” Estrogens and androgens are crucial for male fertility.
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August 2013 in “Fertility and Sterility” Finasteride may improve sperm count in subfertile men with low sperm count.
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May 2007 in “PubMed” Early diagnosis and treatment of haemochromatosis are crucial for reversing organ damage and improving fertility.
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March 2016 in “The Journal of Urology” Male infertility often lacks thorough investigation, potentially missing reversible causes.
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June 2008 in “Acta Cirurgica Brasileira” Finasteride causes sperm production decrease in Mesocricetus auratus.
August 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” Finasteride, at doses of 5mg or higher, may negatively affect male fertility by reducing the expression of certain genes involved in sperm production.
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September 2011 in “International Urology and Nephrology” 2 citations
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December 2001 in “PubMed” June 2014 in “The Journal of Urology” 10 citations
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September 2015 in “Folia Histochemica Et Cytobiologica” Finasteride treatment in male rats can reduce fertility and affect sperm development in their offspring.
January 2018 in “日本薬理学会年会要旨集 =” Stopping finasteride improves sperm quality but not semen volume in young men.
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November 1976 in “Annals of Internal Medicine” Sickle cell anemia causes hormone issues and delayed puberty due to testicular failure.
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August 1987 in “Andrology” Men with low or no sperm count have lower salivary testosterone levels, and saliva testing can measure their testosterone well.
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January 2011 in “Yearbook of Urology” Stopping finasteride can improve sperm count in infertile men.
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January 2004 in “Revista do Hospital das Clínicas” Finasteride may worsen infertility in men with existing issues, but stopping it can improve sperm health.