July 2016 in “Reactions Weekly” Cyproterone and finasteride reduced hypersexuality but caused serious side effects.
38 citations
,
December 2010 in “Fertility and Sterility” Finasteride may cause male infertility, stopping it can help.
Certain medications can negatively impact male fertility.
3 citations
,
February 2018 in “Human Reproduction” A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.
5 citations
,
September 2024 in “Stem Cell Research & Therapy” Sertoli cell transplants can reduce inflammation and improve sperm quality.
112 citations
,
July 2012 in “The Journal of Sexual Medicine” Finasteride may cause long-lasting sexual side effects.
3 citations
,
April 2012 in “Fertility and Sterility” Finasteride may cause infertility in rats by affecting epididymis and sperm function.
April 2022 in “The Journal of Sexual Medicine” Treating hematospermia can improve sexual function and reduce anxiety.
48 citations
,
February 2006 in “Molecular and Cellular Endocrinology” 5α-reductase inhibitors may reduce male fertility and could be used for male contraception.
2 citations
,
October 1999 in “The Journal of Urology”
February 2012 in “European Urology Supplements” Finasteride for hair loss may cause long-lasting sexual side effects in young males.
April 2020 in “The FASEB Journal” Finasteride may cause lasting sexual issues by altering specific genes in human cells.
October 2021 in “International Journal of Andrology” Finasteride, a hair loss drug, has unaddressed sexual side effects due to the manufacturer's inadequate safety measures and lack of additional studies.
Finasteride causes reproductive malformations in male rats.
61 citations
,
April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
3 citations
,
February 2013 in “The Journal of Sexual Medicine” Finasteride may cause lasting sexual side effects, but more research is needed.
26 citations
,
March 2001 in “PubMed” Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.
January 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Finasteride may be a promising treatment for recurrent priapism in sickle cell anemia.
June 2011 in “Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)” Estrogens and androgens are crucial for male fertility.
2 citations
,
January 2011 in “Yearbook of Urology” Stopping finasteride can improve sperm count in infertile men.
March 2013 in “Reactions Weekly” A man's fertility improved after he stopped taking finasteride but worsened again when he restarted the medication.
30 citations
,
January 2020 in “Fertility and Sterility” Finasteride can cause serious side effects in some men, needing more research for treatment.
34 citations
,
January 2004 in “PubMed” DHT deficiency in rats reduces sperm content and affects testis structure over time.
September 2014 in “PubMed Central” BPH treatments can cause sexual side effects affecting quality of life.
November 2024 in “Scientific Reports” Chemotherapy for male germ cell tumors often leads to hypogonadism and related symptoms.
July 2023 in “The journal of sexual medicine” Anabolic-androgenic steroids harm male hormone levels, sperm, metabolism, and can cause acne, hair loss, and breast growth.
February 2026 in “European Urology”
2 citations
,
October 2000 in “The Journal of Urology” Finasteride daily doesn't affect sperm production or semen in young men.
October 2020 in “Reactions Weekly” Finasteride can cause multiple side effects like tremors, dry skin, and rapid aging.
September 2022 in “Translational Andrology and Urology” Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.