June 2021 in “Archives of Advances in Biosciences” Finasteride reduces sperm count and quality and alters hormone levels in mice.
26 citations
,
October 2014 in “Andrologia” Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.
June 1998 in “Biomedicine & Pharmacotherapy” Medical treatments like chemotherapy and radiotherapy can harm sperm production, so freezing sperm before treatment is important for men who want children later.
2 citations
,
January 2014 in “Elsevier eBooks” The document explains how sperm cells are produced, the role of testosterone in this process, and how toxins can reduce sperm count and fertility.
72 citations
,
September 1975 in “Biology of Reproduction” Most zinc in rat sperm is in the tail, linked to structures similar to hair keratin.
18 citations
,
May 2002 in “BJUI” Finasteride doesn't change rat testicle weight or sperm production.
January 2013 in “Reproductive Biology”
28 citations
,
May 2015 in “Addiction Biology” Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.
25 citations
,
July 2013 in “Actas Dermo-Sifiliográficas” Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.
21 citations
,
January 2020 in “General and Comparative Endocrinology” Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
5 citations
,
June 2008 in “Acta Cirurgica Brasileira” Finasteride causes sperm production decrease in Mesocricetus auratus.
4 citations
,
September 2020 in “Andrologia” Oregano extract helps fix testis and sperm damage caused by finasteride.
3 citations
,
August 2015 in “Acta Scientiarum Biological Sciences” Neem extract is safe for pregnant or lactating rats at tested doses.
August 2025 in “Journal of the Pakistan Medical Association” Skin issues might be linked to infertility.
14 citations
,
March 2020 in “Cold Spring Harbor Perspectives in Biology” Mouse spermatogenesis shows that stem cells can behave flexibly and move widely in open environments.
58 citations
,
March 2013 in “Human Reproduction Update” Products should be called 'sperm-safe' only after thorough, well-designed tests.
110 citations
,
August 2016 in “Drugs” Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.
December 2023 in “Urogenital tract infection” Seminal bacteria can lower sperm quality in subfertile men.
46 citations
,
September 2014 in “Steroids” Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
February 2025 in “Iraqi Journal of Science” PCOS patients have higher LDH and lower cortisol, dopamine, zinc, and vitamin D3, which may contribute to their symptoms and obesity.
January 2024 in “Wiadomości Lekarskie” Male sperm disorders significantly contribute to infertility.
5 citations
,
August 1987 in “Andrology” Men with low or no sperm count have lower salivary testosterone levels, and saliva testing can measure their testosterone well.
6 citations
,
November 2018 in “Journal of molecular histology” Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.
June 2011 in “Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)” Estrogens and androgens are crucial for male fertility.
3 citations
,
February 2018 in “Human Reproduction” A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.
4 citations
,
January 2023 in “Andrology” The testes produce sperm and hormones essential for male development.
2 citations
,
June 2024 in “Parasites & Vectors” Chronic T. gondii infection may harm male fertility.
June 2026 in “The Journal of Sexual Medicine” Rare seminoma found in a 33-year-old woman with atypical genitalia and no Y chromosome.
October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” A small BOTOX dose improved sperm production and movement in older mice.
3 citations
,
July 2024 in “Urology Annals” Younger Klinefelter Syndrome patients have a better chance of successful sperm extraction.