February 2020 in “Journal of chemical neuroanatomy” Researchers found a way to make rat hair follicle cells start turning into motor neuron-like cells, but couldn't fully turn them into working motor neurons.
15 citations
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December 2015 in “PLoS ONE” Fibroblasts can be mistaken for neural cells, so functional validation is needed.
7 citations
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July 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Human skin can be reconnected to nerves using stem cells, which may help with skin health and healing.
January 2018 in “VCU Scholars Compass (Virginia Commonwealth University)” Desmosomes are crucial for skin and heart development, and JNK may help regulate them.
6 citations
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September 2023 in “Experimental physiology” A special receptor in sensory nerve endings helps control how they respond to stretching.
1 citations
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January 2018 Sphingosine 1-phosphate and its receptor S1PR3 are key in controlling mechanical pain.
June 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Dopaminergic neurons in the gut have distinct subtypes, some releasing both dopamine and acetylcholine.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” HSD11b1 affects skin nerves and increases non-histaminergic itch.
1 citations
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June 2024 in “Skin Research and Technology” Human dermal fibroblast proteins help restore nerves during healing.
January 2008 in “Durham e-Theses (Durham University)” Hair follicle stem cells are similar to mesenchymal stem cells and can become neural-like cells under certain conditions.
89 citations
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May 2005 in “Stem Cells” Mouse skin has special cells in the epidermis that decrease with age and are linked to keratinocyte stem cells.
9 citations
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October 1994 in “Brain Research” Fetal sheep develop skin nerve pathways and responses to touch and heat between 75 and 134 days of gestation.
227 citations
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February 1989 in “The Journal of Comparative Neurology” CGRP-IR axons may help maintain and renew tissues.
32 citations
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February 2019 in “eLife” BMP signaling is essential for the development of touch domes.
50 citations
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February 2007 in “Expert Opinion on Biological Therapy” Hair follicle stem cells could help repair nerves and avoid ethical issues linked to embryonic stem cells.
The data suggests that dosing differences can help manage spasticity in patients with upper motor neuron dysfunction.
April 2009 in “The FASEB Journal” Keratin biomaterials from human hair help nerve regeneration by activating Schwann cells.
April 2023 in “Journal of Investigative Dermatology” PRP can improve hair growth in people with hair loss, but more research is needed.
64 citations
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May 2015 in “Cell Cycle” Hair follicle stem cells can become heart muscle cells.
August 2019 in “Journal of Investigative Dermatology” Frog skin cells need the protein desmoplakin for proper development and cell layer formation.
1 citations
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January 2001 in “PubMed” Mechanoreceptors convert physical touch into electrical signals through specialized nerve structures.
September 2024 in “Journal of the American Academy of Dermatology” Oxytocin receptors are found in skin cells near touch and pain neurons.
41 citations
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April 2009 in “Journal of comparative neurology” P2X3-IR fibers are widespread in rat skin and likely help detect pain.
9 citations
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January 2018 in “Stem Cells International” Deer antler stem cell fluid helps regenerate tissue better than fat-derived stem cell fluid.
6 citations
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September 2009 in “European journal of histochemistry” CD90 is present on specific cells in dog hair follicles.
2 citations
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April 2014 in “PubMed” Epidermal neural crest stem cells from hair follicles can help repair nerve injuries.
4 citations
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June 2021 in “Basic and Clinical Neuroscience Journal” Rat hair follicle stem cells can improve nerve repair and muscle function after injury.
19 citations
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February 2013 in “Journal of Investigative Dermatology” Touch domes in human skin are complex sensory structures not directly linked to hair.
Rat hair follicle bulge cells can become nerve and glial cells, showing potential for neuroprotection.
92 citations
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March 2010 in “Gerontology” Deer antler regeneration offers insights for human limb regeneration and scar reduction.