Hair germ cells differ from epidermal cells in keratin expression, and specific keratins form after hair differentiation.
409 citations
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May 1991 in “Genes & Development” TGF-alpha affects skin thickness, hair growth, and may contribute to psoriasis and papilloma formation.
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May 2001 in “Proceedings of the National Academy of Sciences” Overexpression of COX-2 in mice skin causes abnormal skin and hair development.
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October 2001 in “Experimental Dermatology” The nude gene is important for skin and hair development.
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August 2025 in “Journal of Radiation Research” Understanding skin reactions to radiation has improved, helping to reduce injuries and prevent skin cancer.
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July 2022 in “Frontiers in Cell and Developmental Biology” The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.
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June 2011 in “PubMed” Alopecia should be treated as a medical condition because it may increase the risk of serious diseases and psychological issues.
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October 2012 in “Journal of Morphology” Reptile skin hardens by layering beta-proteins on keratin.
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April 2001 in “Journal of Investigative Dermatology” The keratin tail is crucial for skin structure and function.
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May 2023 in “Cell Proliferation” TGF-β and FGF pathways are crucial for skin development and regeneration.
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July 2015 in “European journal of histochemistry” Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.
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September 2011 in “Scanning” Multiphoton microscopy effectively images mouse skin layers and structures.
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February 2024 in “International Journal of Molecular Sciences” Negative Pressure Wound Therapy speeds up wound healing by reducing inflammation and promoting skin cell growth.
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March 2023 in “Aggregate” A new hydrogel with micronized amnion helps achieve better, scar-free skin healing.
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May 2022 in “International journal of molecular sciences” Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.
January 2025 in “PLoS ONE” Aligned membranes improve wound healing by reducing scars and promoting skin regeneration.
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April 2008 in “Current opinion in cell biology” Notch signalling helps skin cells differentiate and prevents tumors.
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June 2011 in “Molecular and cellular endocrinology” Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
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March 2008 in “Journal of Cell Science” The mutation causing Hutchinson-Gilford progeria syndrome leads to severe skin problems and early death in mice.
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January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
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October 2003 in “Developmental Biology” Too much Sonic Hedgehog protein stops hair growth in embryos.
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August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
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July 2021 in “Frontiers in Cell and Developmental Biology” Oral mucosa heals with minimal scarring, offering insights for scarless wound healing.
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June 2020 in “International Journal of Molecular Sciences” Notch signaling disruptions can cause various skin diseases.
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August 2020 in “Cells” TGM3 is important for skin and hair structure and may help diagnose cancer.
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May 2025 in “MedComm” Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
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August 2013 in “Stem Cells and Development” The method increases stem-like cells for better skin regeneration.
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November 2024 in “International Journal of Molecular Sciences” YAP and TAZ proteins control skin cell growth and repair.
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January 2010 in “Dermatology Research and Practice” Desmosomes are crucial for human skin development, increasing in density as the skin matures.
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September 2013 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.