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Using 5-α-reductase inhibitors before treatment improves outcomes for patients with metastatic renal cell carcinoma.

5α-reductase inhibitors like finasteride and dutasteride effectively treat BPH by reducing DHT levels.

The SNP rs6457452 is linked to a higher risk of alopecia areata in Koreans.

OR2AT4 helps reduce aging and cell damage in human skin cells.

Compound 15a was effective in inhibiting 5α-reductase.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

The hr gene is linked to hair loss in Valle del Belice sheep.

FCER1A and RGS1 may help diagnose and treat systemic lupus erythematosus.

SFRP2 boosts Wnt3a/β-catenin signals in hair growth cells, with stronger effects in beard cells than scalp cells.

Neuroactive steroids affect cocaine's rewarding effects through the sigma1 receptor.

Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.

New genotype linked to non-classical congenital adrenal hyperplasia found in Italian siblings.

5-alpha reductase inhibitors help with benign prostatic hyperplasia but don't cure it, and more research is needed.

Sfrp2 increases during hair follicle catagen phase and slows keratinocyte growth.

Different body areas have unique skin cell communication patterns, explaining why certain skin diseases occur in specific regions.

Elf5 controls skin cell growth and development, making it a potential target for skin treatments.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

The study identified a key protein involved in producing underarm odor and found ways to inhibit it.

Removing anthrax toxin receptor 1 in pigs prevents Senecavirus A infection and causes a rare disease similar to GAPO syndrome.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.

AKR1C enzymes in scalp glands decrease with age, possibly affecting hair loss.

5alpha-reductase inhibitors like finasteride and dutasteride effectively treat BPH by reducing DHT, offering symptom relief and potential future uses.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

High CRP levels could indicate vitamin D deficiency in people with alopecia areata.

SCD1 is crucial for skin health and overall energy balance.

The trichohyalin gene is located at chromosomal region 1q21 with other skin-related protein genes.

Defects in certain proteins cause major heart abnormalities during early development.

Mutations in the enzyme don't significantly change how it binds to its specific substances.