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AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe symptoms and organ damage in mice.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

New compounds were made that are promising for prostate cancer therapy.

Genetically modified rats help reveal how vitamin D affects bone and skin health.

Somatic BHD mutations are rare in Japanese renal tumors.

Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.

LX-38 is a safer drug option for hair loss and prostate issues without hormonal side effects.

LX-38 is a safer drug option for treating prostate issues and hair loss without hormonal side effects.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

A new genetic change in the DSC3 gene is linked to a rare condition causing hair loss and skin blisters in a child.

Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

RXR agonists may promote hair growth in humans.

Arg1+ macrophages may play a role in Alopecia Areata, offering new treatment targets.

PLA2R1 overexpression harms kidney cells by stopping their growth cycle.

The TIP1 gene is crucial for normal plant cell growth in Arabidopsis.

Vitamin D receptor may help protect against UV-induced skin cancer.

A specific genetic trait in tumor cells is linked to longer survival without disease in certain lymphoma patients.

Retinoic acid affects male and female muscle energy use and function differently.

PDRN helps repair tissue and improve wound healing with a high safety profile.

A man had a severe allergic reaction to sulfasalazine, with symptoms improving after treatment and follow-up.

A new mutation in the KRT86 gene causes a hair disorder with variable expression.

Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.

The VDR gene polymorphism does not affect BDNF levels in autoimmune thyroiditis and hypothyroidism patients.

An 11-year-old girl with a rare skin disorder also had cornea issues and dry eye, needing careful management.