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Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Targeting impaired Nrf2 signaling might help treat hidradenitis suppurativa early on.

Escin may help treat hair loss by boosting a specific cell growth pathway.

Solid Lipid Particle technology makes retinol more stable, effective, and gentle on the skin.

SOCS1 and SOCS3 help control skin inflammation and are important for developing treatments for skin diseases.

RXRa is crucial for Th2 immune cell development and may link nutrition to immune health.

SOX9 is crucial for cell development and repair but can cause fibrosis and cancer if misregulated.

LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.

SGK1 is important in cancer growth and treatment resistance, and targeting it could improve therapies.

SOX4 is crucial for the development of melanoma.

Adding soybean oil to Nonomuraea dietziae increases production of a beneficial compound by improving metabolism and enzyme systems.

As people age, certain enzymes in scalp glands decrease, affecting hair health.

Sex steroids influence skin appendage function and neoplasm development, with changes in AR and ERalpha in certain gland neoplasms.

The three adipokines—leptin, adiponectin, and resistin—are present in various cells of normal dog skin.

OsPHR2 gene causes excessive phosphate in rice shoots, affecting plant growth and root development.

Increasing EGR1 levels makes hair root cells grow faster.

Vitamin D receptor and hairless protein are essential for hair growth.

TRF1 is crucial for creating and maintaining stem cells and marks both pluripotent and adult stem cells.

Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.

C-reactive protein helps monocytes stick to blood vessel cells by causing oxidative stress.

A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.