November 2020 in “TURKDERM” Hormonal treatments effectively manage acne in some women, especially with specific hormonal issues.
1 citations
,
November 2022 in “Journal of the Academy of Consultation-Liaison Psychiatry”
14 citations
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March 2017 in “Brain research” Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.
60 citations
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December 2013 in “PLoS ONE” EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.
2 citations
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August 2011 in “Cochrane Database of Systematic Reviews”
52 citations
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January 1995 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Low-dose isotretinoin is as effective as conventional doses for acne and has fewer side effects.
March 2002 in “Clin-Alert” In 2002, various drugs caused serious side effects, including vitamin B12 deficiency, heart issues, blindness, hypersexuality, allergic reactions, blood clotting problems, pupil dilation, capillary leak syndrome, muscle breakdown, hepatitis, skin reactions, and lupus.
60 citations
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November 2009 in “General and Comparative Endocrinology” Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
10 citations
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January 2017 in “Skin Pharmacology and Physiology” Finasteride may cause vitiligo, sexual issues, and depression; better treatments and predicting side effects needed.
305 citations
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March 2008 in “AJP Endocrinology and Metabolism” SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.
January 2011 in “The Journal of Secondary Vocational Education” Isotretinoin treatment in teens with acne can cause hormonal changes, leading to menstrual irregularity and increased hirsutism.
76 citations
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December 1997 in “Fertility and Sterility” Finasteride reduces hair growth better, but spironolactone has more side effects.
August 2023 in “Revista Ibero-Americana de Humanidades, Ciências e Educação” People with skin conditions like psoriasis and eczema have higher anxiety levels.
13 citations
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January 2017 in “Annals of dermatology/Annals of Dermatology” Simvastatin/ezetimibe may help some patients with severe alopecia areata regrow hair.
4 citations
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September 2010 in “Medical Hypotheses”
9 citations
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June 2020 in “Actas Dermo-Sifiliográficas” Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.
4 citations
,
June 2003 in “Fertility and Sterility” Finasteride doesn't affect ovulation in normal women.
18 citations
,
November 2011 in “Health & Social Work” Lupus patients often face depression and anxiety due to physical changes, with education and insurance affecting their mental health.
2 citations
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July 2019 in “Journal of psychology & clinical psychiatry” Zinc helps reduce the severity of depression.
8 citations
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April 2004 in “The Journal of Urology” Doxazosin and finasteride negatively affect sexual function in men with BPH.
March 2021 in “Clin-Alert” The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.
16 citations
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October 1994 in “The Journal of Steroid Biochemistry and Molecular Biology” Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
July 2025 in “Scientific Reports” Pioglitazone, Trimipramine, and Dimetindene may be repurposed to treat psoriasis.
14 citations
,
January 2020 in “Archivio Italiano di Urologia e Andrologia” Finasteride helps with prostate symptoms but may cause sexual side effects.
8 citations
,
April 2021 in “Journal of Clinical Investigation” Finasteride reduces opioid use and withdrawal symptoms in animals.
May 2024 in “Brain disorders” Agmatine may help reduce seizures linked to hormone changes in female rats.
3 citations
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January 2000 Psychoactive drugs can help treat skin conditions linked to psychological issues.
32 citations
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October 2015 in “Frontiers in Cellular Neuroscience” DHT is needed for long-term depression, while E2 is needed for full long-term potentiation in male rat brains.