November 2010 in “Clin-Alert” Monitoring for adverse effects in clinical treatments is crucial.
2 citations
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March 2016 in “Düşünen Adam” Switching from escitalopram to duloxetine improved hair loss.
February 2025 in “Iranian journal of pharmaceutical research”
April 2026 in “Brain Sciences” Finasteride may cause depression and suicidal thoughts, especially in young men.
July 2024 in “Behavioural Brain Research” Long-term finasteride treatment reduces depression and brain issues in obese male rats.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Acne treatment, including isotretinoin, improves quality of life and does not worsen depression.
33 citations
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January 2016 in “Skin appendage disorders” The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.
January 2007 in “Edward Elgar eBooks” TSPO might help treat anxiety and depression.
19 citations
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July 2023 in “Neuroscience & Biobehavioral Reviews” Endogenous neurosteroids may set a baseline mood.
1 citations
,
August 2015 in “Current Sexual Health Reports” 5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.
12 citations
,
April 2018 in “Physiology & Behavior” Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.
August 2012 in “Reactions Weekly” Finasteride users with sexual issues often experience depression.
4 citations
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May 2019 in “The World Journal of Men's Health” Taking 5 alpha reductase inhibitor medication slightly increases the risk of depression, especially as you get older.
June 2025 in “Reactions Weekly” Finasteride may increase the risk of depression and suicidal thoughts.
April 2023 in “European urology open science” Urologists should screen for mental health issues before and during finasteride treatment.
November 2023 in “Magna Scientia Advanced Research and Reviews” Trazodone might help reverse post finasteride syndrome.
2 citations
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September 2009 in “Hormone Molecular Biology and Clinical Investigation” Low dose finasteride decreases certain steroids, possibly increasing depression risk.
May 2024 in “Reactions weekly”
5 citations
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October 2020 in “Brain Research Bulletin” Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.
5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.
Men with sexual side effects from finasteride may face higher risks of depression and suicidal thoughts.
May 2024 in “Reactions weekly” 3 citations
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February 2019 in “Der Urologe” Medications for benign prostatic syndrome can cause cognitive issues and depression.
April 2021 in “Reactions Weekly” Finasteride increases risk of depression, possibly suicidal thoughts, and sexual dysfunction.
May 2024 in “Reactions weekly” January 2004 in “Data Archiving and Networked Services (DANS)” Finasteride blocks progesterone's effect on brain activity linked to epilepsy.
1 citations
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October 2009 in “Current psychiatry” Choose treatments for sex offenders based on individual needs, using hormonal and nonhormonal options to reduce sexual drive.
January 2008 in “Journal of Medicinal Chemistry” Finasteride may cause sexual and psychological side effects by affecting an enzyme related to epinephrine.
Certain medications, especially nervous system drugs, can cause insomnia, with risks varying by age and gender.
March 2020 in “European Journal of Pediatric Dermatology” Isotretinoin can cause gynecomastia by lowering testosterone levels.