7 citations
,
April 2021 in “Journal of Clinical Psychopharmacology” Finasteride may increase the risk of depression, anxiety, and suicidal thoughts.
35 citations
,
March 2013 in “American Journal of Medical Genetics Part B Neuropsychiatric Genetics” SRD5A2 gene variations affect PTSD symptoms differently in males and females.
April 2023 in “European urology open science” Urologists should screen for mental health issues before and during finasteride treatment.
June 2024 in “Drug and therapeutics bulletin” Finasteride can cause depression, suicidal thoughts, and lasting psychiatric and sexual issues.
January 2015 in “International Journal of Nanomedicine” Anionic squarticles can effectively counteract amitriptyline overdose, improving survival rates.
27 citations
,
April 2008 in “Neuroscience Letters” Olanzapine reduces stress-related anxiety in rats when given acutely.
2 citations
,
October 2002 in “American Journal of Nursing” Taking the same medication under different brand names caused harmful side effects.
111 citations
,
August 2015 in “Reviews in Endocrine and Metabolic Disorders” 5α-reductase inhibitors may cause persistent sexual dysfunction and depression, needing more research on long-term effects.
1 citations
,
November 2015 in “Cochrane library” 5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.
March 2025 in “Journal of Cosmetic Dermatology” Finasteride use may increase depression and suicide risk, especially at 1 mg, so monitoring is advised.
66 citations
,
January 2008 in “Pharmacology Biochemistry and Behavior” AC-5216 reduces anxiety in mice through neurosteroids affecting GABAA receptors.
88 citations
,
October 2002 in “Journal of Dermatology” Finasteride for hair loss may cause depression, affecting sleep and relationships.
5 citations
,
October 2020 in “Brain Research Bulletin” Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.
January 2012 in “Anales (Reial Acadèmia de Medicina de la Comunitat Valenciana)” SRD5A2 enzyme expression varies in benign prostates and can be influenced by inflammation, affecting treatment options.
December 2023 in “Alzheimer's & dementia” Finasteride may help reduce anxiety and depression in elderly but might cause depression in young men.
24 citations
,
May 2015 in “Schizophrenia Research” A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.
24 citations
,
July 2015 in “International Journal of Molecular Sciences” Fluoxetine may help reduce fat by limiting stem cell growth and fat cell formation.
2 citations
,
January 2015 in “Journal of Investigative Dermatology”
29 citations
,
September 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity” Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.
73 citations
,
July 2013 in “The Journal of Sexual Medicine” Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.
1 citations
,
March 2020 in “Journal of Pharmacological Sciences” Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.
January 2004 in “Data Archiving and Networked Services (DANS)” Finasteride blocks progesterone's effect on brain activity linked to epilepsy.
14 citations
,
June 1995 in “The Journal of Clinical Endocrinology and Metabolism”
February 2024 in “Urology” Certain medications, especially Paroxetine, Tamsulosin, and Finasteride, are linked to ejaculatory disorders.
May 2018 in “KU ScholarWorks (The University of Kansas)” Targeting 5α-reductase type 1 may help manage Tourette-like symptoms.
64 citations
,
March 2008 in “Neuropsychopharmacology”
April 2024 in “Journal of psychiatric research” Short-term finasteride use in male rats caused anxiety, depression, and memory problems.
2 citations
,
April 2020 in “Journal of Mind and Medical Sciences” Psychotropic drugs can interact with natural products, affecting their effectiveness and safety.
October 2024 in “Journal of Neuroscience Research” Long-term Finasteride treatment reduces depression better than short-term treatment in rats.
1 citations
,
June 2014 in “L Endocrinologo” Finasteride can cause lasting sexual and mood issues even after stopping the drug.